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  1. A significant update was made to both the Global Initiative for Asthma (GINA) in 2019 and the National Heart Lung and Blood Institute (NHLBI) asthma guidelines in 2020 for mild asthma. These groups no longer r...

    Authors: Beth A. Zerr, Jacklyn M. Kruse and Jon J. Glover
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:27
  2. Hereditary alpha-tryptasemia (HαT) is an autosomal dominant disorder estimated to affect 5% of the population. High baseline tryptase level is a consistent finding, but there is a great variability of clinic m...

    Authors: Vicky Le Blanc and Wade T. A. Watson
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:26
  3. Systemic corticosteroid (SCS) use remains widespread among patients with severe asthma, despite associated complications.

    Authors: Thomas B Casale, Thomas Corbridge, Guillaume Germain, François Laliberté, Sean D MacKnight, Julien Boudreau, Mei S Duh and Arijita Deb
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:25
  4. Asthma exacerbations are a leading cause of pediatric hospitalizations despite multiple efforts to educate patients and families on disease course and medication management. Asthma education in the pediatric e...

    Authors: Kina Goodman, Rosa I. Arriaga, Rawan Korman, Farzina Zafar, Cal Stephens, Polly Kumari, Karthika Jayaprakash, Anne M. Fitzpatrick, Nicholas Cooper and Claudia R. Morris
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:24
  5. Circular RNA (circRNA) has the potential to serve as a crucial regulator in the progression of bronchial asthma. The objective of this investigation was to elucidate the functional dynamics of the circ_0070934...

    Authors: Ziqi Ding, Xinru Xiao, Liang Fan, Zhengdao Mao, Chuang Sun, Na Li and Qian Zhang
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:23
  6. The poly-sensitization to Hymenoptera venom makes it difficult to select genuine allergens for immunotherapy and increases patients’ costs. The objective of this study was to determine the culprit allergen in ...

    Authors: Mohammad Hassan Bemanian, Raheleh Shokouhi Shoormasti, Saba Arshi, Mahsa Jafari, Sima Shokri, Morteza Fallahpour, Mohammad Nabavi and Fatemeh Zaremehrjardi
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:22
  7. While the impacts of atopic dermatitis (AD) on maternal and child sleep outcomes have been previously explored, less is known about the associations between infantile AD and sleep quality and quantity.

    Authors: Zoe Harbottle, Amanda Nötzel, Michael A. Golding, Manvir Bhamra, Isac Kopsch, Erik Wilking, Marina Jonsson, Elissa M. Abrams, Michelle A. Halbrich, Elinor Simons, Leslie E. Roos, Jill A. Keddy-Grant, Thomas V. Gerstner, Jo-Anne St-Vincent, Sandra Ekström and Jennifer L. P. Protudjer
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:21
  8. Self-reported penicillin allergy labels are common and often inaccurate after assessment. These labels can lead to reduced use of first-line beta-lactam antibiotics and worse outcomes. We measured the impact o...

    Authors: Adhora Mir, Derek Lanoue, Veronica Zanichelli, Carl van Walraven, Timothy Olynych, Caroline Nott and Derek MacFadden
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:20
  9. Eosinophilic gastritis (EoG) has rarely been reported in conjunction with gluten-sensitive enteropathy (GSE). When this does occur, patients typically present with gastrointestinal symptoms. To our knowledge, ...

    Authors: Zhirong Du, Zixi Wang, Weixun Zhou, Jia Yin and Yuxiang Zhi
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:19
  10. In this letter to the editor, we present questionnaire-based data assessing the patient journey of adults with moderate–severe Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) in the USA and five European cou...

    Authors: Jeremiah Hwee, Lauren Lee, Mark Small, Steven G. Smith, Victoria S. Benson and Shiyuan Zhang
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:17
  11. Correlations between mitochondrial DNA (mtDNA) and allergic rhinitis (AR) have not been reported before. This study aimed to better understand the mitochondrial genome profile with AR and to investigate the as...

    Authors: Huajie Yuan, Lingling Wang, Song Wang, Linge Li, Qingping Liu, Yan Wang, Yuping Yang and Hua Zhang
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:16
  12. While a connection has been established between serum interleukin-6 (IL-6) levels and the IL-6 gene (− 174G/C) polymorphism in allergic diseases such as asthma, its specific association with severe asthma remains...

    Authors: Mona Al-Ahmad, Asmaa Ali, Ahmed Maher and Mohammad Z. Haider
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:15
  13. Chronic Rhinosinusitis (CRS) is a paranasal sinus inflammatory disease and is divided into two subgroups defined as CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). CRSwNP displays a T hel...

    Authors: Javad Nazari, Faezeh Shahba, Negin Jafariaghdam, Saleh Mohebbi, Saba Arshi, Mohammad Hassan Bemanian, Morteza Fallahpour, Sima Shokri, Fatemeh Atashrazm, Saeed Amini, Maryam Roomiani, Mahnaz Jamee, Pegah Babaheidarian, Majid Khoshmirsafa and Mohammad Nabavi
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:14
  14. According to the Th1/Th2 paradigm, the expansion of Th1-type clones in individuals with type 1 diabetes results in reduced Th2-type clones, preventing the development of atopic diseases and vice versa. However...

    Authors: Júlia Marchatto Kamei, Raissa Dias Maués, Gabriel de Oliveira Silva, Alessandra Helena Machado, Erika Megumi Hoshino, Fabiana Menezes Bacchiega, Laís Mota Furtado Sena and Carlos Antonio Negrato
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:12
  15. Mepolizumab, the first widely available anti-interleukin 5 biologic, targets eosinophilic inflammation and has been shown in clinical trials to reduce exacerbations, oral corticosteroid dependence, and healthc...

    Authors: Kenneth R. Chapman, Kathryn Cogger, Erin Arthurs, Callahan LaForty, Shane Golden, Bradley Millson, Koyo Usuba and Christopher Licskai
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:11
  16. Obstructive sleep apnea (OSA) occurs more commonly in asthma patients than in the general population because these conditions share some comorbidities. In Japan, the prevalence of OSA in the general population...

    Authors: Mina Yasuda, Kazunori Tobino, Norihiro Harada, Ryunosuke Ooi, Takuto Sueyasu, Saori Nishizawa, Miyuki Munechika, Kohei Yoshimine, Yuki Ko, Yuki Yoshimatsu, Kosuke Tsuruno, Hiromi Ide and Kazuhisa Takahashi
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:10
  17. Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E (IgE) -mediated food allergy predominantly observed in infants and characterized by the delayed onset of vomiting following ingesti...

    Authors: Hunter Hall, Sara Anvari, Fallon Schultz, Olubukola Ojuola and Nicholas L. Rider
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:9
  18. Proteinase-activated receptor 2 (PAR-2) is a G-protein coupled receptor associated with many inflammatory diseases, including asthma. We have shown an association between PAR-2 expression in peripheral blood m...

    Authors: Nami Shrestha Palikhe, Qahir Haji, Emily Mack, Tristan Sinnatamby, Andrew J. Sandford, Lisa Cameron and Harissios Vliagoftis
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:8
  19. Inborn errors of immunity (IEIs) are a group of conditions whereby parts of the immune system are missing or dysfunctional. Once thought to primarily be a pediatric disorder, it is now estimated that more than...

    Authors: Joanne J. F. Wang, Arün Dhir, Kyla J. Hildebrand, Stuart E. Turvey, Robert Schellenberg, Luke Y. C. Chen, Persia Pourshahnazari and Catherine M. Biggs
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:6
  20. Poor sleep health is associated with increased asthma morbidity and mortality. Accelerometers have been validated to assess sleep parameters though studies using this method in patients with asthma are sparse ...

    Authors: Varun Sharma, Helen Clare Ricketts, Femke Steffensen, Anna Goodfellow, Duncan S Buchan and Douglas C Cowan
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:5
  21. H. pylori is a gram-negative bacterium that is usually acquired in childhood and can persistently colonize the gastric mucosa of humans, affecting approximately half of the world’s population. In recent years,...

    Authors: Mengmeng Liu, Yong Wang and Bing Du
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:4
  22. Interleukin (IL)-36 family is closely associated with inflammation and consists of IL-36α, IL-36β, IL-36γ, and IL-36Ra. The role of IL-36 in the context of asthma and asthmatic phenotypes is not well character...

    Authors: Jinyan Li, Zhengda Wang, Hongna Dong, Yuqiu Hao, Peng Gao and Wei Li
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:3
  23. Allergic asthma and rhinitis (AR) are closely linked, with a significant proportion of AR patients developing asthma. Identification of the early signs of comorbidity of AR and asthma can enable prompt treatme...

    Authors: Myung Woul Han, Song Hee Kim, Inbo Oh, Yang ho Kim and Jiho Lee
    Citation: Allergy, Asthma & Clinical Immunology 2024 20:1
  24. Increasing evidence suggests that hormone therapy (HT) and obesity exert an influence on allergic rhinitis (AR). It is important to investigate the association and interactions between HT, BMI, and AR in perim...

    Authors: Jingyi Liu, Tingting Ma, Xiaoxue Wang, Wenpei Bai and Xueyan Wang
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:107
  25. Real-world data on subcutaneous C1INH (C1INH[SC]) usage and patient-level impacts on hereditary angioedema (HAE)-related outcomes and quality of life (QoL) are both lacking and challenging to generate using co...

    Authors: William Lumry, Timothy Craig, John Anderson, Marc Riedl, Henry Li, Raffi Tachdjian, Michael Manning, Paolo Bajcic, Frank Rodino, Sam Wang, Thomas R. Sexton and Jonathan A. Bernstein
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:105
  26. Several biologics are now approved in the US as add-on treatments for chronic rhinosinusitus with nasal polyps (CRSwNP). This cross-sectional, retrospective, real-world study aimed to characterize treatment pa...

    Authors: Jared Silver, Elizabeth Packnett, Julie Park and Arijita Deb
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:104
  27. Non-esophageal eosinophilic gastrointestinal disorder (non-EoE-EGID) is a rare disease in which eosinophils infiltrate parts of the gastrointestinal tract other than the esophagus; however, the number of patie...

    Authors: Mitsuru Tsuge, Kenji Shigehara, Kazuhiro Uda, Seiji Kawano, Masaya Iwamuro, Yukie Saito, Masato Yashiro, Masanori Ikeda and Hirokazu Tsukahara
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:103
  28. The diagnosis of Alpha-gal Syndrome (AGS) is based on the presence of symptoms after being exposed to potential sources of alpha-gal together with values ​​of specific IgE (sIgE) to alpha-gal ≥ 0.1 kUA/L or ≥ ...

    Authors: Adrián Germán-Sánchez, Ana Alonso-Llamazares, Fernando García-González, Bakai Matala-Ahmed, Ceny Solani Melgar-Reyes and Ignacio Antepara-Ercoreca
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:102
  29. Childhood atopic dermatitis can have a negative effect on caregivers’ quality of life and stress levels due to the burdensome nature of its treatment. Given that the condition often emerges in infancy, atopic ...

    Authors: Ayel Luis R. Batac, Kaitlyn A. Merrill, Michael A. Golding, Manvir Bhamra, Zoe Harbottle, Isac Kopsch, Erik Wilking, Marina Jonsson, Sandra Ekström, Elissa M. Abrams, Michelle A. Halbrich, Elinor Simons, Leslie E. Roos, Jill A. Keddy-Grant, Thomas V. Gerstner, Jo-Anne St-Vincent…
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:100
  30. Food allergies (FA) can detrimentally impact physical, emotional, and psychological quality of life (QoL) among pediatric patients. Given the changes from childhood into adolescence, the impact of FA on QoL li...

    Authors: Diem-Tran I. Nguyen, Kathleen Pitts, Kristen A. Staggers and Carla M. Davis
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:99
  31. Human placental extract (HPE) has been documented to facilitate the healing of certain disorders including allergy. However, the effects of HPE on the functionality of mast cells, a critical cell type in aller...

    Authors: Tongqian Wu, Jingjing He, Shirong Yan, Jing Li, Ke Chen, Dingshan Zhang, Mingliang Cheng, Zou Xiang and Yu Fang
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:98
  32. Although numerous studies have suggested a negative correlation between Helicobacter pylori (H. pylori) infection and allergies, there has been limited research on the relationship between H. pylori infections an...

    Authors: Shuxian Wang, Xiaokang Wang, Jiaqi Liu, Yaqian Li, Minghui Sun, Guoqiang Zhu and Xiaofang Zhu
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:97
  33. Hypersensitivity pneumonitis (HP) is usually caused by the inhalation of avian and fungal proteins. The present study assesses a cohort of Urban Pest Surveillance and Control Service (UPSCS) workers with high ...

    Authors: Silvia Sánchez-Díez, Xavier Muñoz, Tomás Montalvo, Iñigo Ojanguren, Christian Romero-Mesones, Juan Carlos Senar, Victor Peracho-Tobeña and María-Jesús Cruz
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:96
  34. Most asthma diagnoses and patient care take place in primary care settings. Electronic medical records (EMRs) offer an opportunity to utilize technology to improve asthma diagnosis and care. The purpose of thi...

    Authors: Max Moloney, Alison Morra, Rachael Morkem, John Queenan, Samir Gupta, Teresa To, Geneviève Digby, David Barber and M. Diane Lougheed
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:95
  35. Food ladders are tools designed to facilitate home-based dietary advancement in children with food allergies through stepwise exposures to increasingly allergenic forms of milk and egg. Several studies have no...

    Authors: Alanna Chomyn, Edmond S. Chan, Joanne Yeung, Scott Cameron, Gilbert T. Chua, Timothy K. Vander Leek, Brock A Williams, Lianne Soller, Elissa M. Abrams, Raymond Mak and Tiffany Wong
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:94
  36. Osimertinib has emerged as an important tool in the treatment of non-small cell lung cancers (NSCLC) with certain activating mutations of epidermal growth factor receptor (EGFR). However, Osimertinib may cause...

    Authors: Michael Lopez, Garo Hagopian, Linda Doan, Benjamin J. Lee, Nathan W. Rojek, Janellen Smith, Sai-Hong Ignatius Ou, Yesim Yilmaz Demirdag and Misako Nagasaka
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:93
  37. Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a rare but severe and sometimes fatal adverse drug reaction that is known to occur with a number of antiepileptic drugs. It often follo...

    Authors: Khanh Duy Doan, Adeyinka Akinsanya, Matthew Kuhar and Hector Mesa
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:92
  38. There is an urgent need to understand the interplay between SARS-CoV-2 and HIV to inform risk-mitigation approaches for HIV-infected individuals.

    Authors: Shima Shahbaz, Wendy Sligl, Mohammed Osman and Shokrollah Elahi
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:91
  39. Dupilumab, omalizumab, and mepolizumab are the three biologics currently approved for use in CRSwNP in Canada. Despite evidence of efficacy, their cost-effectiveness, which is a key factor influencing prescrib...

    Authors: Michael Yong, Keshinisuthan Kirubalingam, Martin Y. Desrosiers, Shaun J. Kilty and Andrew Thamboo
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:90
  40. Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects children and adults. Poor treatment adherence in AD requires interventions to promote self-management; patient education in chronic di...

    Authors: Bethany Wilken, M. Zaman and Y. Asai
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:89
  41. Penicillin allergy is the most commonly reported drug allergy in the US. Despite evidence demonstrating that up to 90% of labels are incorrect, scalable interventions are not well established. As part of a lar...

    Authors: Esra Alagoz, Megan Saucke, Prakash Balasubramanian, Paul Lata, Tyler Liebenstein and Sujani Kakumanu
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:88
  42. Current management of food protein-induced enterocolitis syndrome (FPIES) involves strict avoidance of the offending food for 12–18 months, followed by oral food challenge (OFC) under physician supervision. OF...

    Authors: Linlei Ye, Tiffany Wong, Elana Lavine, Victoria E. Cook and Stephanie C. Erdle
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:87
  43. Activated phosphoinositide3-kinase (PI3K) δ syndrome 1 (APDS1) is a novel inborn errors of immunity (IEIs) caused by heterozygous gain of function mutations in PI3Kδ catalytic p110δ (PIK3CD). APDS1 has a spect...

    Authors: Lu Jiang, Xiaohan Hu, Qiang Lin, Ruyue Chen, Yunyan Shen, Yun Zhu, Qinying Xu and Xiaozhong Li
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:86
  44. Canada has high immunoglobulin (IG) product utilization, raising concerns about appropriate utilization, cost and risk of shortages. Currently, there is no national set of standardized IG guidelines, and consi...

    Authors: Megan Harmon, Kiarash Riazi, Jeannie Callum, Donald M. Arnold, Rebecca Barty, Davinder Sidhu, Nancy M. Heddle, Laurie MacLeod and Na Li
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:85

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