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  1. Review

    Asthma and the microbiome: defining the critical window in early life

    Asthma is a chronic inflammatory immune disorder of the airways affecting one in ten children in westernized countries. The geographical disparity combined with a generational rise in prevalence, emphasizes th...

    Leah T. Stiemsma and Stuart E. Turvey

    Allergy, Asthma & Clinical Immunology 2017 13:3

    Published on: 6 January 2017

  2. Case report

    Polyethylene glycol as a cause of anaphylaxis

    Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food.

    Katharina Wylon, Sabine Dölle and Margitta Worm

    Allergy, Asthma & Clinical Immunology 2016 12:67

    Published on: 13 December 2016

  3. Case report

    Anaphylaxis to supplemental oral lactase enzyme

    Anaphylactic reactions involving IgE mediated hypersensitivity have been frequently reported for a number of uncommon foods. However, cases of anaphylaxis to over the counter vitamins and oral supplements have...

    M. R. Voisin and R. Borici-Mazi

    Allergy, Asthma & Clinical Immunology 2016 12:66

    Published on: 13 December 2016

  4. Meeting abstracts

    AllerGen’s 8th research conference

    Marie-Claire Arrieta, Andrea Arevalos, Leah Stiemsma, Marta E. Chico, Carlos Sandoval, Minglian Jin, Jens Walter, Phil Cooper, Brett Finlay, Emilie Bernatchez, Matthew J. Gold, Anick Langlois, Pascale Blais-Lecours, Caroline Duchaine, David Marsolais, Kelly M. McNagny…

    Allergy, Asthma & Clinical Immunology 2016 12(Suppl 2):63

    Published on: 8 December 2016

    This article is part of a Supplement: Volume 12 Supplement 2

  5. Research

    Gene mutations responsible for primary immunodeficiency disorders: A report from the first primary immunodeficiency biobank in Iran

    Primary immunodeficiency (PID) is a heterogeneous group of inheritable genetic disorders with increased susceptibility to infections, autoimmunity, uncontrolled inflammation and malignancy. Timely precise diag...

    Saba Sheikhbahaei, Roya Sherkat, Dirk Roos, Majid Yaran, Somayeh Najafi and Alireza Emami

    Allergy, Asthma & Clinical Immunology 2016 12:62

    Published on: 2 December 2016

  6. Research

    Analysis of feline and canine allergen components in patients sensitized to pets

    Component resolved allergen diagnosis allows for a precise evaluation of the sensitization profiles of patients sensitized to felines and canines. An accurate interpretation of these results allows better insi...

    Natalia Ukleja-Sokołowska, Ewa Gawrońska-Ukleja, Magdalena Żbikowska-Gotz, Ewa Socha, Kinga Lis, Łukasz Sokołowski, Andrzej Kuźmiński and Zbigniew Bartuzi

    Allergy, Asthma & Clinical Immunology 2016 12:61

    Published on: 30 November 2016

  7. Research

    Prevalence of beta-lactam allergy: a retrospective chart review of drug allergy assessment in a predominantly pediatric population

    Research suggests that 90% of patients labeled beta-lactam allergic are able to tolerate penicillins following further assessment. This study aims to define and describe the frequency of true beta-lactam aller...

    Elissa M. Abrams, Andrew Wakeman, Tom V. Gerstner, Richard J. Warrington and Alexander G. Singer

    Allergy, Asthma & Clinical Immunology 2016 12:59

    Published on: 29 November 2016

  8. Review

    Lymphocyte Kv1.3-channels in the pathogenesis of chronic obstructive pulmonary disease: novel therapeutic implications of targeting the channels by commonly used drugs

    In patients with chronic obstructive pulmonary disease (COPD), over-activated T-lymphocytes produce pro-inflammatory cytokines and proliferate in situ in the lower airways and pulmonary parenchyma, contributin...

    Itsuro Kazama and Tsutomu Tamada

    Allergy, Asthma & Clinical Immunology 2016 12:60

    Published on: 29 November 2016

  9. Research

    Usefulness of component resolved analysis of cat allergy in routine clinical practice

    Cat allergy is of great importance, and its prevalence is increasing worldwide. Cat allergens and house dust mite allergens represent the major indoor allergens; however, they are ubiquitous. Cat sensitization...

    Katharina Eder, Sven Becker, Marion San Nicoló, Alexander Berghaus and Moritz Gröger

    Allergy, Asthma & Clinical Immunology 2016 12:58

    Published on: 15 November 2016

  10. Research

    Prospective evaluation of testing with baked milk to predict safe ingestion of baked milk in unheated milk-allergic children

    Cow’s milk allergy is one of the most common food allergies affecting young children. A subset of milk-allergic individuals can eat baked milk without allergic symptoms which is beneficial in terms of prognost...

    Allison Kwan, Maria Asper, Sasson Lavi, Elana Lavine, David Hummel and Julia E. Upton

    Allergy, Asthma & Clinical Immunology 2016 12:54

    Published on: 24 October 2016

  11. Research

    Predictors of allergen sensitization in Singapore children from birth to 3 years

    Immune responses in allergic diseases begin with allergen sensitization, which usually occurs in childhood. Allergen sensitization involves a complex interplay of genetic and environmental factors, and sensiti...

    Evelyn Xiu Ling Loo, Jordan Zheng Ting Sim, Anne Goh, Oon Hoe Teoh, Yiong Huak Chan, Seang Mei Saw, Kenneth Kwek, Peter D. Gluckman, Keith M. Godfrey, Hugo Van Bever, Yap Seng Chong, Bee Wah Lee, Michael S. Kramer and Lynette Pei-chi Shek

    Allergy, Asthma & Clinical Immunology 2016 12:56

    Published on: 24 October 2016

  12. Research

    Th17 responses are not altered by natural exposure to seasonal allergens in pollen-sensitive patients

    Allergic rhinitis affects 10–30 % of the global population and this number is likely to increase in the forthcoming years. Moreover, it commonly co-exists with allergic asthma as a chronic allergic respiratory...

    Agata Schramm, Barbara Jasiewicz-Honkisz, Grzegorz Osmenda, Grzegorz Wilk, Mateusz Siedlinski, Agnieszka Sagan, Pawel T. Matusik, Joanna Maciag, Tomasz Sliwa, Marta Czesnikiewicz-Guzik and Tomasz P. Mikolajczyk

    Allergy, Asthma & Clinical Immunology 2016 12:55

    Published on: 24 October 2016

  13. Research

    Clinical validation of controlled exposure to birch pollen in the Environmental Exposure Unit (EEU)

    The Environmental Exposure Unit (EEU) in Kingston, Ontario, Canada is a controlled allergen challenge facility (CACF) that has been previously clinically validated for the use of ragweed and grass pollen in cl...

    Anne K. Ellis, Mena Soliman, Lisa M. Steacy, Daniel E. Adams, Barnaby Hobsbawn and Terry J. B. Walker

    Allergy, Asthma & Clinical Immunology 2016 12:53

    Published on: 19 October 2016

  14. Review

    Genetic and epigenetic studies of atopic dermatitis

    Atopic dermatitis (AD) is a chronic inflammatory disease caused by the complex interaction of genetic, immune and environmental factors. There have many recent discoveries involving the genetic and epigenetic ...

    Lianghua Bin and Donald Y. M. Leung

    Allergy, Asthma & Clinical Immunology 2016 12:52

    Published on: 19 October 2016

  15. Review

    Air pollution, epigenetics, and asthma

    Exposure to traffic-related air pollution (TRAP) has been implicated in asthma development, persistence, and exacerbation. This exposure is highly significant as large segments of the global population resides...

    Hong Ji, Jocelyn M. Biagini Myers, Eric B. Brandt, Cole Brokamp, Patrick H. Ryan and Gurjit K. Khurana Hershey

    Allergy, Asthma & Clinical Immunology 2016 12:51

    Published on: 19 October 2016

  16. Research

    Interacting effects of obesity, race, ethnicity and sex on the incidence and control of adult-onset asthma

    To improve care and control for patients with adult-onset asthma, a better understanding of determinants of their risk and outcomes is important. We investigated how associations between asthma, asthma control...

    Corinna Koebnick, Heidi Fischer, Matthew F. Daley, Assiamira Ferrara, Michael A. Horberg, Beth Waitzfelder, Deborah Rohm Young and Michael K. Gould

    Allergy, Asthma & Clinical Immunology 2016 12:50

    Published on: 19 October 2016

  17. Research

    Adrenal suppression in children treated with swallowed fluticasone and oral viscous budesonide for eosinophilic esophagitis

    Adrenal suppression (AS), a glucocorticoid (GC) side effect associated with significant morbidity, is well described related to inhaled corticosteroid therapy for asthma. Swallowed topical glucocorticoid thera...

    Alexandra Ahmet, Eric I. Benchimol, Ellen B. Goldbloom and Janice L. Barkey

    Allergy, Asthma & Clinical Immunology 2016 12:49

    Published on: 10 October 2016

  18. Research

    Co-exposure to zymosan A and heat-inactivated Asian sand dust exacerbates ovalbumin-induced murine lung eosinophilia

    Epidemiological studies have implicated Asian sand dust (ASD) in the increased prevalence of respiratory disorders, including asthma. It has been observed that fungal elements such as β-glucan can be adsorbed ...

    Kaori Sadakane, Takamichi Ichinose, Masataka Nishikawa, Hirohisa Takano and Takayuki Shibamoto

    Allergy, Asthma & Clinical Immunology 2016 12:48

    Published on: 10 October 2016

  19. Research

    Two-weeks-sustained unresponsiveness by oral immunotherapy using microwave heated cow’s milk for children with cow’s milk allergy

    Several studies have reported that oral immunotherapy (OIT) is effective for children with cow’s milk (CM) allergy. These studies reported the efficacy of OIT in terms of desensitization, but did not describe ...

    Masaya Takahashi, Shoichiro Taniuchi, Kazuhiko Soejima, Yasuko Hatano, Sohsaku Yamanouchi and Kazuanri Kaneko

    Allergy, Asthma & Clinical Immunology 2016 12:44

    Published on: 26 August 2016

    The Erratum to this article has been published in Allergy, Asthma & Clinical Immunology 2016 12:57

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