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  1. Research

    Breakthrough attacks in patients with hereditary angioedema receiving long-term prophylaxis are responsive to icatibant: findings from the Icatibant Outcome Survey

    Patients with hereditary angioedema (HAE) due to C1-inhibitor deficiency (C1-INH-HAE) experience recurrent attacks of cutaneous or submucosal edema that may be frequent and severe; prophylactic treatments can ...

    Werner Aberer, Marcus Maurer, Laurence Bouillet, Andrea Zanichelli, Teresa Caballero, Hilary J. Longhurst, Amandine Perrin and Irmgard Andresen

    Allergy, Asthma & Clinical Immunology 2017 13:31

    Published on: 5 July 2017

  2. Meeting abstracts

    Abstracts from the 10th C1-inhibitor deficiency workshop

    Alvin H. Schmaier, Marco Cicardi, Avner Reshef, Dumitru Moldovan, Attila Mócsai, Margarita López-Trascasa, Alberto López Lera, Nancy J. Brown, Anastasios E. Germenis, Rafael Filippelli-Silva, Diego A. Duarte, Renan P. Martin, Camila L. Veronez, Michel Bouvier, Michael Bader, Claudio M. Costa-Neto…

    Allergy, Asthma & Clinical Immunology 2017 13(Suppl 2):29

    Published on: 15 June 2017

    This article is part of a Supplement: Volume 13 Supplement 2

  3. Research

    A case series evaluating the serological response of adult asthma patients to the 23-valent pneumococcal polysaccharide vaccine

    Asthma is an independent risk factor for invasive pneumococcal disease; however, the immune response of adult asthma patients to pneumococcal vaccination is unknown. We explore the serologic response of patien...

    C. R. Laratta, K. Williams, D. Vethanayagam, M. Ulanova and H. Vliagoftis

    Allergy, Asthma & Clinical Immunology 2017 13:27

    Published on: 7 June 2017

  4. Research

    Maternal sensitivity and social support protect against childhood atopic dermatitis

    Many studies have identified associations between qualities of maternal–child relationships and childhood asthma, but few have examined associations with childhood atopic dermatitis (AD), a common precursor to...

    Nicole L. Letourneau, Anita L. Kozyrskyj, Nela Cosic, Henry N. Ntanda, Lubna Anis, Martha J. Hart, Tavis S. Campbell and Gerald F. Giesbrecht

    Allergy, Asthma & Clinical Immunology 2017 13:26

    Published on: 26 May 2017

  5. Case Report

    Systemic mastocytosis with KIT V560G mutation presenting as recurrent episodes of vascular collapse: response to disodium cromoglycate and disease outcome

    Mastocytosis are rare diseases characterized by an accumulation of clonal mast cells (MCs) in one or multiple organs or tissues. Patients with systemic mastocytosis (SM), whose MCs frequently arbor the activat...

    Iolanda Conde-Fernandes, Rita Sampaio, Filipa Moreno, José Palla-Garcia, Maria dos Anjos Teixeira, Inês Freitas, Esmeralda Neves, Maria Jara-Acevedo, Luis Escribano and Margarida Lima

    Allergy, Asthma & Clinical Immunology 2017 13:21

    Published on: 24 April 2017

  6. Research

    Regulation of Th2 responses by different cell types expressing the interleukin-31 receptor

    Interleukin-31 (IL-31) is a recently identified cytokine produced by Th2 cells that is involved in the development of atopic dermatitis-induced skin inflammation and pruritus. Its receptor, IL-31RA, is express...

    Saburo Saito, Ayana Aoki, Iwao Arai, Shinya Takaishi, Haruyasu Ito, Nobutake Akiyama and Hiroshi Kiyonari

    Allergy, Asthma & Clinical Immunology 2017 13:23

    Published on: 17 April 2017

  7. Research

    Preconception allergen sensitization can induce B10 cells in offspring: a potential main role for maternal IgG

    The mechanisms through which allergies can be inhibited after preconception immunization with allergens are not fully understood. We aimed to evaluate whether maternal immunization can induce a regulatory B (B...

    Marília Garcia de Oliveira, Luana de Mendonça Oliveira, Aline Aparecida de Lima Lira, Fábio da Ressureição Sgnotto, Alberto José da Silva Duarte, Maria Notomi Sato and Jefferson Russo Victor

    Allergy, Asthma & Clinical Immunology 2017 13:22

    Published on: 17 April 2017

  8. Meeting abstracts

    Canadian Society of Allergy and Clinical Immunology annual scientific meeting 2016

    Mohammad A. Alsayegh, Hanan Alshamali, Mousa Khadada, Amanda Ciccolini, Anne K. Ellis, Diana Quint, William Powley, Laurie Lee, Yahya Fiteih, Shairaz Baksh, Harissios Vliagoftis, Sebastien K. Gerega, Brad Millson, Katia Charland, Stephane Barakat, Xichun Sun…

    Allergy, Asthma & Clinical Immunology 2017 13(Suppl 1):16

    Published on: 7 April 2017

    This article is part of a Supplement: Volume 13 Supplement 1

  9. Research

    Sputum cell counts to manage prednisone-dependent asthma: effects on FEV1 and eosinophilic exacerbations

    Prednisone dependence in asthma is usually described based on clinical and spirometric characteristics. It is generally believed that these patients have frequent exacerbations and lose lung function rapidly b...

    Afia Aziz-Ur-Rehman, Angira Dasgupta, Melanie Kjarsgaard, Frederick E. Hargreave and Parameswaran Nair

    Allergy, Asthma & Clinical Immunology 2017 13:17

    Published on: 4 April 2017

  10. Research

    Consumer preferences for food allergen labeling

    Food allergen labeling is an important tool to reduce risk of exposure and prevent anaphylaxis for individuals with food allergies. Health Canada released a Canadian food allergen labeling regulation (2008) an...

    Carlo A. Marra, Stephanie Harvard, Maja Grubisic, Jessica Galo, Ann Clarke, Susan Elliott and Larry D. Lynd

    Allergy, Asthma & Clinical Immunology 2017 13:19

    Published on: 4 April 2017

  11. Research

    Efficacy and safety of setipiprant in seasonal allergic rhinitis: results from Phase 2 and Phase 3 randomized, double-blind, placebo- and active-referenced studies

    Antagonism of chemoattractant receptor-homologous molecule on T-helper type-2 cells (CRTH2), a G-protein coupled receptor for prostaglandin D2, could be beneficial for treating allergic disorders. We present f...

    Paul Ratner, Charles P. Andrews, Frank C. Hampel, Bruce Martin, Dale E. Mohar, Denis Bourrelly, Parisa Danaietash, Sara Mangialaio, Jasper Dingemanse, Abdel Hmissi and Jay van Bavel

    Allergy, Asthma & Clinical Immunology 2017 13:18

    Published on: 4 April 2017

  12. Research

    Elevated expression of TIGIT on CD3+CD4+ T cells correlates with disease activity in systemic lupus erythematosus

    It is well-known that lymphocytes play an important role in systemic lupus erythematosus (SLE). T cell immunoreceptor with Ig and immunoreceptor tyrosine-based inhibitory domains (TIGIT) is one of immunosuppre...

    Qing Luo, Jianqing Ye, Lulu Zeng, Xue Li, Le Fang, Beihua Ju, Zikun Huang and Junming Li

    Allergy, Asthma & Clinical Immunology 2017 13:15

    Published on: 28 February 2017

  13. Review

    Gene therapy for primary immune deficiencies: a Canadian perspective

    The use of gene therapy (GT) for the treatment of primary immune deficiencies (PID) including severe combined immune deficiency (SCID) has progressed significantly in the recent years. In particular, long-term...

    Xiaobai Xu, Chetankumar S. Tailor and Eyal Grunebaum

    Allergy, Asthma & Clinical Immunology 2017 13:14

    Published on: 27 February 2017

  14. Case Report

    An avoidable cause of thymoglobulin anaphylaxis

    Thymoglobulin® (anti-thymocyte globulin [rabbit]) is a purified pasteurised, gamma immune globulin obtained by immunisation of rabbits with human thymocytes. Anaphylactic allergic reactions to a first injectio...

    S. Brabant, A. Facon, F. Provôt, M. Labalette, B. Wallaert and C. Chenivesse

    Allergy, Asthma & Clinical Immunology 2017 13:13

    Published on: 23 February 2017

  15. Letter to the editor

    Allergic rhinitis: the eligible candidate to mite immunotherapy in the real world

    As standard drug treatment of allergic rhinitis (AR) is not completely satisfactory, allergen immunotherapy (AIT) represents the only current treatment with the potential to modify the natural history. House d...

    Giorgio Ciprandi, Valentina Natoli, Paola Puccinelli and Cristoforo Incorvaia

    Allergy, Asthma & Clinical Immunology 2017 13:11

    Published on: 21 February 2017

  16. Letter to the editor

    Primum non nocere—first do no harm. And then feed peanut

    The Addendum Guidelines for the Prevention of Peanut Allergy in the United StatesReport of the NIAID-Sponsored Expert Panel were developed to build on previous food allergy guidelines after several key studies d...

    Kyla Jade Hildebrand, Elissa Michele Abrams, Timothy K. Vander Leek, Julia Elizabeth Mainwaring Upton, Douglas P. Mack, Linda Kirste, Christine McCusker and Sandeep Kapur

    Allergy, Asthma & Clinical Immunology 2017 13:7

    Published on: 8 February 2017

  17. Research

    Prevalence of allergen sensitization in 1000 adults in Saskatchewan

    The prevalence of sensitization varies geographically based on multiple environmental factors including humidity. The aim of this study was to determine the prevalence of atopy in symptomatic adults. More impo...

    Stacey D. Lok, Beth E. Davis and Donald W. Cockcroft

    Allergy, Asthma & Clinical Immunology 2017 13:9

    Published on: 8 February 2017

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