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Table 2 Correlates of Higher Lumbosacral Bone Density Z-Score Values in ICS-Treated Asthmatic Adults*

From: Asthma and Therapeutics: Inhaled Corticosteroids, Corticosteroid Osteoporosis, and the Risk of Fracture in Chronic Asthma

Correlates of Higher Bone Density p Value (ANCOVA)
Larger cumulative lifetime dose of ICS .002
Lower current daily dose of ICS .013
Fewer years of prednisone exposure .032
Greater physical activity .042
More years of supplemental estrogen use .058
  1. Adapted from Toogood JH et al. [4]
  2. ANCOVA = analysis of covariance; ICS = inhaled corticosteroid. *N = 69. Age: 59.9 ± 13.3 yr (SD).
  3. Years of steroid exposure (mean ± SD): prednisone = 10.7 ± 9.7 yr, ICS = 10.1 ± 5.5 yr.