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Table 3 RR for asthma hospitalization in childhood according to gestational age and estimated fetal growth

From: Birth weight, gestational age, fetal growth and childhood asthma hospitalization

Fetal development variables

Cases

Cumulative incidence (%)

Crude RR

Adjusted RR* (95% CI)

22-28 weeks

    

  SGA

180

9.09

1.14

1.02 (0.86-1.21)

  AGA

527

7.96

1

1 (ref)

  LGA

30

5.43

0.71

0.71 (0.46-1.11)

Z-score per decreased of SD

-

-

1.04

1.02 (0.99-1.04)

29-32 weeks

    

  SGA

359

6.15

1.20

1.07 (0.94-1.22)

  AGA

1,010

5.05

1

1 (ref)

  LGA

47

2.96

0.58

0.60 (0.43-0.85)

Z-score per decreased of SD

-

-

1.06

1.04 (1.02-1.07)

33-36 weeks

    

  SGA

675

4.27

1.26

1.06 (0.97-1.17)

  AGA

5,409

3.43

1

1 (ref)

  LGA

387

3.41

0.99

0.94 (0.84-1.05)

Z-score per decreased of SD

-

-

1.05

1.03 (1.01-1.04)

37-38 weeks

    

  SGA

860

3.56

1.22

1.15 (1.07-1.24)

  AGA

20,735

2.93

1

1 (ref)

  LGA

1,467

3.43

1.17

1.03 (0.97-1.09)

Z-score per decreased of SD

-

-

0.99

1.02 (1.01-1.03)

39-41 weeks

    

  SGA

2,349

3.01

1.12

1.12 (1.07-1.17)

  AGA

85,611

2.71

1

1 (ref)

  LGA

3,095

3.06

1.13

1.06 (1.02-1.10)

Z-score per decreased of SD

-

-

0.99

1.02 (1.01-1.03)

42-45 weeks

    

  SGA

455

2.51

1.07

1.11 (0.98-1.25)

  AGA

8,449

2.36

1

1 (ref)

  LGA

138

2.83

1.20

1.15 (0.95-1.40)

Z-score per decreased of SD

-

-

1.00

1.02 (0.99-1.05)

  1. *Adjusted for country of residence, maternal age at delivery, maternal social status, parity, mode of delivery, sex of the child, calendar year of birth and family history of asthma.