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Table 4 RR for asthma hospitalization and medication in childhood according to birth weight, gestational age and fetal growth in Denmark, 1993-2005

From: Birth weight, gestational age, fetal growth and childhood asthma hospitalization

Fetal development variables

Asthma hospitalization

Asthma medication

 

Cases

Cumulative incidence (%)

Crude RR

Adjusted RR* (95% CI)

Cases

Cumulative incidence (%)

Crude RR

Adjusted RR* (95% CI)

Birth weight

        

  <1000 g

94

13.58

2.64

2.82 (2.12-3.74)

306

34.06

2.00

1.94 (1.75-2.15)

  1000-1499 g

184

9.01

1.91

1.71 (1.42-2.06)

624

27.12

1.63

1.51 (1.39-1.65)

  1500-1999 g

318

7.76

1.64

1.41 (1.21-1.64)

1,107

24.23

1.45

1.37 (1.28-1.47)

  2000-2499 g

812

6.87

1.46

1.30 (1.17-1.44)

2,950

22.30

1.34

1.29 (1.22-1.36)

  2500-2999 g

2,919

5.29

1.12

1.10 (1.03-1.18)

11,142

18.79

1.13

1.11 (1.07-1.16)

  3000-3499 g

8,099

5.01

1.06

1.07 (1.02-1.13)

30,145

16.89

1.02

1.01 (0.98-1.04)

  3500-3999 g

8,500

4.72

1

1 (ref)

32,242

16.43

1

1 (ref)

  4000-4499 g

4,045

4.89

1.04

1.01 (0.95-1.08)

14,984

16.55

1.00

0.99 (0.95-1.02)

  4500-4999 g

869

4.74

1.01

1.02 (0.92-1.12)

3,165

16.59

1.00

1.00 (0.95-1.05)

  ≥5000 g

135

5.56

1.18

1.15 (0.91-1.45)

463

16.48

1.01

0.99 (0.89-1.08)

Birth weight per 1000-g decrease

-

-

1.17

1.15 (1.11-1.19)

-

-

1.13

1.11 (1.10-1.13)

Gestational age

        

  22-28 weeks

129

11.72

2.34

2.37 (1.87-2.99)

412

30.69

1.86

1.78 (1.64-1.94)

  29-32 weeks

301

8.65

1.79

1.49 (1.29-1.72)

1,084

25.67

1.56

1.45 (1.36-1.54)

  33-36 weeks

1,318

6.36

1.32

1.20 (1.10-1.30)

5,021

21.90

1.33

1.26 (1.22-1.30)

  37-38 weeks

4,464

5.67

1.17

1.14 (1.08-1.21)

16,967

18.69

1.13

1.10 (1.08-1.13)

  39-41 weeks

17,616

4.79

1

1 (ref)

65,682

16.44

1

1 (ref)

  42-45 weeks

2,147

4.61

0.96

0.94 (0.88-1.01)

7,962

17.40

1.05

1.05 (0.95-1.16)

GA per reduced week

-

-

1.06

1.05 (1.04-1.06)

-

-

1.04

1.04 (1.03-1.05)

Birth weight for gestational age

        

  SGA

1,055

6.36

1.29

1.20 (1.10-1.31)

3,776

21.15

1.25

1.19 (1.14-1.24)

  AGA

23,784

4.94

1

1 (ref)

89,263

17.02

1

1 (ref)

  LGA

1,136

5.32

1.07

1.11 (0.99-1.24)

4,089

17.34

1.02

1.04 (0.99-1.09)

Z-score per decreased of SD

-

-

1.03

1.01 (0.99-1.03)

-

-

1.03

1.02 (1.01-1.03)

  1. *Adjusted for maternal age at delivery, maternal social status, parity, mode of delivery, sex of the child, calendar year of birth and family history of asthma.
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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