Short-term prophylaxis | |||||
---|---|---|---|---|---|
Medication class | Example | Dose | Approval | ||
Canada | US | Europe | |||
C1 INH replacement (plasma derived) | Berinert | 10 to 20 U/kg body weight or 1000 U IV* | ✓ | ||
Cinryze | 500-1500 U IV 1 hour prior to event | ✓ | ✓ | ||
Attenuated androgens | Danazol | 200 mg PO TID × 5-7 d before procedure, and 4 d post-procedure | ✓ |