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Table 3 Mean change in Asthma Control Questionnaire and Pediatric Asthma Caregivers Quality of Life Questionnaire

From: Effectiveness of montelukast administered as monotherapy or in combination with inhaled corticosteroid in pediatric patients with uncontrolled asthma: a prospective cohort study

Age group

Treatment group

Total

Montelukast monotherapy

Montelukast + ICS

Mean

SD

Mean

SD

Mean

SD

All patients

ACQ score*

Change between Week 4 and Baseline

−0.95

0.88

−1.12

1.03

−1.08

1.00

Change between Week 12 and Baseline

−1.15

0.79

−1.40

1.09

−1.34

1.03

PACQLQ score*

Change between Week 4 and Baseline

0.98

1.12

1.34

1.34

1.25

1.30

Change between Week 12 and Baseline

1.13

1.04

1.78

1.36

1.63

1.32

Emotional function *

Change between Week 4 and Baseline

0.90

1.14

1.25

1.32

1.17

1.29

Change between Week 12 and Baseline

1.02

1.01

1.71

1.41

1.55

1.36

Activity limitation *

Change between Week 4 and Baseline

1.16

1.32

1.53

1.61

1.44

1.55

Change between Week 12 and Baseline

1.38

1.34

1.94

1.51

1.81

1.49

Pre-School patients

ACQ score*

Change between Week 4 and Baseline

−0.89

1.10

−1.38

1.08

−1.26

1.11

Change between Week 12 and Baseline

−1.13

0.94

−1.56

1.16

−1.45

1.12

PACQLQ score*

Change between Week 4 and Baseline

1.01

1.19

1.73

1.42

1.55

1.40

Change between Week 12 and Baseline

1.18

1.06

2.03

1.30

1.82

1.30

Emotional function *

Change between Week 4 and Baseline

0.88

1.16

1.60

1.41

1.42

1.39

Change between Week 12 and Baseline

1.05

0.95

1.94

1.34

1.72

1.31

Activity limitation *

Change between Week 4 and Baseline

1.29

1.40

2.02

1.62

1.84

1.60

Change between Week 12 and Baseline

1.47

1.47

2.24

1.45

2.05

1.49

School aged patients

ACQ score*

Change between Week 4 and Baseline

−1.01

0.64

−0.93

0.94

−0.94

0.88

Change between Week 12 and Baseline

−1.18

0.64

−1.27

1.02

−1.25

0.95

PACQLQ score*

Change between Week 4 and Baseline

0.96

1.08

1.04

1.20

1.02

1.17

Change between Week 12 and Baseline

1.09

1.03

1.58

1.37

1.47

1.31

Emotional function *

Change between Week 4 and Baseline

0.92

1.14

0.99

1.19

0.97

1.18

Change between Week 12 and Baseline

1.00

1.08

1.53

1.44

1.41

1.38

Activity limitation *

Change between Week 4 and Baseline

1.04

1.26

1.15

1.49

1.13

1.44

Change between Week 12 and Baseline

1.29

1.23

1.70

1.52

1.61

1.47

  1. * P < 0.001 for all changes from baseline based on Student’s t-test for Paired Observations.
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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