Figure 3

Correlation circle depicting the strength of correlation between Treg genes (red) and Th17 genes (blue) with their respective latent variables (Comp 1 and Comp 2). The Treg genes (red) show a strong negative correlation with the Th17 genes (blue). Vectors drawn from the origin to each of the points (genes) allows one to determine the relationship between genes: 1) if the angle between two vectors is less than 90°, there exists a positive correlation between the two genes, 2) if the angle between two vectors is greater than 90°, there exists a negative correlation between the two genes, and 3) if the angle between two vectors is equal to 90°, the correlation between the two genes is zero.