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Table 3 Association of TZDs with asthma exacerbations and steroid prescriptions in multivariable models *

From: Thiazolidinediones and the risk of asthma exacerbation among patients with diabetes: a cohort study

Event

Any event

Number of events

OR

95%CI

IRR

95%CI

Asthma exacerbation

0.79

0.62 – 0.99

0.81

0.64 – 1.02

Steroid prescription

0.73

0.63 – 0.84

0.68

0.58 – 0.80

  1. *Adjusted for age, gender, race, free care, distance to VA facility, number of primary care encounters, Diagnostic Cost Group score, Diabetes Severity Index score, prior year exacerbations, atrial fibrillation, heart failure, ischemic heart disease, alcohol or drug abuse, and depression, respiratory medications.
  2. Logistic regression with outcome being presence of asthma exacerbation or steroid prescription. Results are presented in odds ratios (OR) and 95% confidence intervals (CI).
  3. Negative binomial regression with outcome being number of asthma exacerbations or number of steroid prescriptions. Results are presented in incidence rate ratios (IRR) and 95% confidence intervals.