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Figure 2 | Allergy, Asthma & Clinical Immunology

Figure 2

From: Maternal immunization with ovalbumin or Dermatophagoides pteronyssinus has opposing effects on FcγRIIb expression on offspring B cells

Figure 2

Increased CD40 expression on offspring B cells induced by maternal immunization. Offspring from (A) OVA- or (B) Dp-immunized mothers were immunized at 3 do with the same antigen used in the maternal immunization and boosted at 13 do. At 20 do, splenic CD19+ B cells were assessed for CD40 expression and the percentage of CD19+ IgM + cells. The control group was composed of offspring from non-immune mothers immunized with OVA or Dp. Representative histograms of CD40 expression for each group are shown (A-B, middle panels). The data are presented as mean (8 to 10 mice per group) ± SEM values. *P ≤ 0.05 compared with the control group.

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