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Figure 2 | Allergy, Asthma & Clinical Immunology

Figure 2

From: Coaggregation of FcεRI with FcγRIIB Inhibits Degranulation but Not Induction of Bcl-2 Family Members A1 and Bim in Mast Cells

Figure 2

Reduction of immunoglobulin E (IgE)-dependent phosphorylation of Akt by FcγRIIB. C57 mast cells were activated as in Figure 1B for the indicated periods of time. Cell lysates were prepared, and the phosphorylation of Akt was analyzed by Western blot with the indicated antibodies. The result is representative of three independent experiments. Ser = serine; Thr = threonine; 2.4G2 Ab = anti-mouse CD16/CD32 (FcγIII/II receptor) monoclonal antibody.

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