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Figure 6 | Allergy, Asthma & Clinical Immunology

Figure 6

From: Epigenetics, Behaviour, and Health

Figure 6

Activation of chromatin by increasing acetylation facilitates demethylation. Acetylation of histones could be increased by either recruitment of histone acetyltransferases (HAT) or pharmacologic inhibition of histone deacetylases with trichostatin A (TSA). Histone acetylation facilitates interaction of demethylases with the DNA and DNA demethylation.

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