Is Obesity Associated with an Increased Risk for Airway Hyperresponsiveness and Development of Asthma?

Table 4 Sex Differences for Airway Hyperresponsiveness Prevalence with Body Mass Index

	*Prevalence of AHR in Subjects with BMI <30 or ≥30*				*Prevalence of AHR in Subjects with BMI <35 or ≥35*				*Prevalence of AHR in Subjects with BMI <40 or ≥40*
*Patient Attribute*	*Female*		*Male*		*Female*		*Male*		*Female*		*Male*
BMI	<30	≥30	<30	≥30	<35	≥35	<35	≥35	<40	≥40	<40	≥40
Total number of subjects	382	230	153	96	496	100	234	31	555	41	250	15
% Methacholine positive	33	42	36	39	34	47	35	59	35	56	35	73
Odds ratio (CI)	1.47 (1.04-2.08)		1.17 (0.70-1.98)		1.72 (1.11-2.65)		2.75 (1.21-6.20)		2.40 (1.26-4.55)		4.82 (1.25-18.6)
p Value	.03		.54		.01		.01		.006		.01
Relative risk	1.27		1.12		1.38		1.71		1.61		2.04
Attributable risk (%)	22		10		28		41		38		51

AHR = airway hyperresponsiveness; BMI = body mass index; CI = confidence interval.

ISSN: 1710-1492