From: Diagnostic evaluation of food-related allergic diseases
Study | No. subjects | % Atopic Dermatitis | Average Age (years) | Study design | Food | Total IgE median kU/L(range) | PPV value %/Specific IgE level (kU/L) | Sens. for IgE level | Spec. for IgE level |
---|---|---|---|---|---|---|---|---|---|
Sampson HA and Ho DG [26] | 196 | 100% | 5.2 | Retrospective DBPCFC in 64% | Cow's milk | 3000 (100-40,000) | 95%/32 | 51% | 98% |
Sampson HA [25] | 62 | 61% | 3.8 | Prospective DBPCFC in 34% | Cow's milk | * | 95%/15 | 57% | 94% |
Garcia-Ara C et al[58] | 170 | 23% | 0.4 | Prospective open controlled challenge in 95% | Cow'smilk | * | 95%/5 | 30% | 99% |
Celik-Bilgili S et al[22] | 398 | 88% | 1.1 | Prospective DBPCFC or open challenge in all | Cow'smilk | * | 90%/88.8 | * | * |
Sampson HA and Ho DG[26] | 196 | 100% | 5.2 | Retrospective DBPCFC in 64% | Hen's egg | 3000 (100-40,000) | 95%/6 | 72% | 90% |
Sampson HA [25] | 75 | 61% | 3.8 | Prospective DBPCFC in 33% | Hen's egg | * | 98%/7 | 61% | 95% |
Celik-Bilgili S et al. [22] | 227 | 88% | 1.1 | Prospective DBPCFC or open challenge in all | Hen's egg | * | 95%/12.6 | * | * |
Boyano Martinez T et al. [61] | 81 | 43% | 1.3 | Prospective, Open controlled challenge in all | Egg white | 40(3-597) | 94%/0.35 | 91% | 77% |
Osterballe M et al[62] | 56 | 100% | 2.2 | Prospective, Open challenge in all | Egg white | * | 100%/1.5 | 60% | 100% |
Sampson HA and Ho DG [26] | 196 | 100% | 5.2 | Retrospective DBPCFC in 64% | Peanut | 3000 (100-40,000) | 95%/15 | 73% | 92% |
Sampson HA[25] | 68 | 61% | 3.8 | Prospective DBPCFC in 2% | Peanut | * | 100%/14 | 57% | 100% |
Maloney JM et al[23] | 234 | 57% | 6.1 | Prospective; clinical history, no challenges | Peanut | * | 99%/13 | 60% | 96% |