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Table 2 Probiotics in treatment of allergies

From: The role of Probiotics in allergic diseases

Author

Year

Study type

Probiotic type

Results

Giovannini

2007

R, PC, DB

L. casei DN-114001

Longertime free from asthmaIrhinitis episodes Less number of episodes of rhinitis episodes

Tamura

2007

R, PC, DB

L. casei strain shirota

No change in allergic rhinitis

Xiao

2007

R, PC, DB

B. Ion gum BBS36

Ameliorate Japanese cedar pollinosis

Brouwer

2006

R, PC, DB

L. rhamnosus I LGG

Lower SCORAD (no different from placebo)

Fälster-Holst

2006

R, PC, DB

L. rhamnosus GG

Lower SCORAD (no different from placebo)

Passeron

2006

R, PC, DB

L. rhamonosus Lcr35 and prebiotic

Decreased SCORAD

Sistek

2006

R, PC, DB

L. rhamnosus, B. lactis

Decreased SCORAD

Xiao

2006

R, PC, DB

B. Iongum BBS36

Ameliorate Japanese cedar pollinosis

Xiao

2006

R, PC, DB

B. Iongum BBS36

Ameliorate Japanese cedar pollinosis

Ciprandi

2005

C

Bacillus clausii spores

Decreased nasal symptoms

Ishida

2005

R, PC, DB

L. acidophil us L-92

Decreased nasal and ocular symptoms

Peng

2005

R, PC, DB

L. plantar um 33

Decreased perennial allergic rhinitis

Viljanen

2005

R, PC, DB

LGG or MIX

Decreased SCORAD

Weston

2005

R, PC, DB

L. ferment um

Decreased SCORAD

Rosenfeldt

2004

R, PC, DB

L. rhamnos us and L. re uteri

Decreased frequency of gastrointestinal symptoms and lactulose:mannitaol ratio

Wang

2004

R, PC, DB

L. paracasei

Decreased frequency and level of bother of allergic rhinitis

Hattori

2003

C

B. breve M-16V

Ameliorate cutaneous and allergic symptoms

Kirjavainen

2003

R, PC, DB

LGG

Decreased SCORAD

Rosenfeldt

2003

R, PC, DB

L. rhamnos us and L. re uteri

Decreased SCORAD

Helin

2002

R, PC, DB

LGG

No effect on birch pollen allergy

Isolauri

2000

R, PC, DB

B. lactis (Bb-12) or LGG

Decreased SCORAD

Majamaa

1997

R, PC, DB

LGG

Decreased SCORAD

Wheeler

1997

R, PC, DB

L. acidophil us

Increased IFN-and less eosinophilia

  1. R = randomized, C = controlled, PC = placebo-controlled, DB = double-blinded, LGG = Lactobacillus GG, SCORAD = severity scoring of atopic dermatitis index