From: On demand treatment and home therapy of hereditary angioedema in Germany - the Frankfurt experience
Incremental IVR [%rise/U/kg bw] | Tmax [hr] | T 1/2 [hr] | MRT [hr] | AUC [U*hr/mL] | Clearance [mL/kg*hr] | Vss [mL/kg] | |
---|---|---|---|---|---|---|---|
Children on Demand n = 6 | 2.2 | 0.6 | 32.9 | 47.5 | 13.4 | 1.1 | 50.0 |
Adults on Demand n = 19 | 2.0 | 1.0 | 39.1 | 56.5 | 16.7 | 0.9 | 56.5 |
Adults IRT n = 15 | 2.9* | 0.5 | 30.9** | 44.6** | 15.7 | 1.0 | 37.5*** |