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Figure 1 | Allergy, Asthma & Clinical Immunology

Figure 1

From: TSLP directly impairs pulmonary Treg function: association with aberrant tolerogenic immunity in asthmatic airway

Figure 1

Pulmonary Treg express functional TSLP-R. A. (Top) TSLP-R expression at protein (% of positive cells) and mRNA levels in HC pulmonary Treg and Teff (n = 14). (Bottom) Representative FACS plots of TSLP-R expression by HC pulmonary Treg and Teff. B. (Left) Phosphorylated STAT5 (pSTAT5) expression, measured by ELISA, in HC pulmonary Treg in response to IL-2, IL-4, IL-7, and TSLP (n = 7). (Right) Representative FACS plots of pSTAT5 expression in HC pulmonary Treg in response to different stimuli. C. pSTAT5 expression, measured by ELISA, in HC pulmonary Teff in response to IL-2, IL-4, IL-7, and TSLP (n = 7). Wilcoxon tests were used for statistical analysis. Horizontal bars represented median values as indicated throughout the figure.

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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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