Figure 5

Histological changes in offspring from mothers exposed to saline or A. fumigatus. a.) Representative histology from lungs of offspring whose mother was treated with saline following 5 doses of A. fumigatus starting at 9-10 weeks. The photomicrograph was taken from a lung section stained with Hematoxylin and Eosin. White arrows point to perivascular and peribronchial inflammation, black arrowheads point to mild arterial muscularization. b.) Representative histology from lung of offspring whose mother was treated with A. fumigatus following 5 doses of A. fumigatus starting at 9-10 weeks. The photomicrograph was taken from a lung section stained with Hematoxylin and Eosin. White arrows point to perivascular and peribronchial inflammation, black arrowheads point to arterial muscularization. No differences were observed among offspring of mice that received diesel exhaust, particles when compared to offspring of mice that received saline. No differences were observed among offspring of mice that received diesel and A. fumigatus, compared to A. fumigatus alone.