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Treatment of initial allergic reactions to peanut inside and outside of health care facilities


Recent studies suggest increased admission rates for food-related anaphylaxis. The only effective treatment for anaphylaxis is prompt administration of epinephrine.


To characterize treatment practices of initial allergic reactions inside and outside health care facilities (HCF).


Individuals with an allergist-confirmed peanut allergy were recruited from the Montreal’s Children Hospital and Canadian food allergy advocacy organizations. Data were collected on initial allergic reactions to peanut and treatment inside and outside HCFs.


Of 751 individuals who had an allergic reaction to peanut, 613 responded (81.6%). Initial reactions were mild in 28.4% (95% CI, 25.0-32.1%), moderate in 50.6% (46.6-54.6%), and severe in 20.9% (17.8-24.3%). Average age of initial reaction was 2.1 years (2.0-2.3). Among participants, 11.6% (9.1-14.7%) were diagnosed with peanut allergy (based on skin and IgE testing) prior to the initial reaction. Of the 613 participants, 32.1% (28.5-36.0%) were treated in HCFs only, 51.7% (47.7-55.7) outside HCFs only, and 16.2% (13.4-19.3%) in both. 21.3% (17.0-26.3%) of all reactions treated in HCFs received epinephrine (table) versus only 3% (1.8-5.1%) treated outside. Of those with moderate or severe initial reactions, 58.2% (53.5-62.8%) were treated in HCFs, and 23.9% (19.1-29.6%) of these received epinephrine. See table 1.

Table 1 Table 1


Almost 50% of individuals with potentially life-threatening initial reactions are not treated in HCFs. Further, for those with moderate and severe reactions treated in HCFs, there is substantial underuse of epinephrine. Thus, it is crucial to establish, distribute, and monitor treatment guidelines that would improve treatment practices of food-related allergic reactions.

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Correspondence to L Soller.

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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution 2.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Soller, L., Ben-Shoshan, M., Fragapane, J. et al. Treatment of initial allergic reactions to peanut inside and outside of health care facilities. All Asth Clin Immun 6, P31 (2010).

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  • Epinephrine
  • Health Care Facility
  • Allergic Reaction
  • Food Allergy
  • Initial Reaction