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Table 1 Association of FLG haplotype and tagSNPs with asthma and atopy (A) and with asthma and atopy that co-occur with the presence of a personal history of atopic dermatitis (B)

From: Association between filaggrin family member genes, asthma, atopy and atopic asthma with atopic dermatitis history in the subjects from the Saguenay-Lac-Saint-Jean founder population

A
SNP Allele Asthma Atopy Atopic asthma
   S:E(S) Z p S:E(S) Z p S:E(S) Z p
rs3126085 A 32.0:50.2 -3.48 0.0005 35.0:49.8 -2.94 0.0033 25.0:37.2 -2.74 0.0061
  G 148.0:129.8 3.48   141.0:126.2 2.94   109.0:96.8 2.74  
B
SNP/Haplotype Allele Asthma and AD Atopy and AD Atopic asthma and AD
   S:E(S) Z p S:E(S) Z P S:E(S) Z p
rs3126085 A 14.0:24.0 -2.94 0.0033 16.0:24.5 -2.59 0.0097 10.0:18.0 -2.74 0.0062
  G 66.0:56.0 2.94   62.0:53.5 2.59   52.0:44.0 2.74  
H1 T G 75.0:66.0 2.61 0.009 75.0:64.0 3.33 0.0009 60.0:51.0 2.94 0.0033
  1. Positives associations were also found between FLG2 rs2065954 and rs3818831 and asthma (p = 0.0033 and p = 0.0016), atopy (p = 0.00009 and p = 0.00006) and atopic asthma (p = 0.0004 and p = 0.0002) in all cases in the presence of AD as well as AD alone (p = 0.0016 and p = 0.0007 respectively).