Table 1 Association of FLG haplotype and tagSNPs with asthma and atopy (A) and with asthma and atopy that co-occur with the presence of a personal history of atopic dermatitis (B)
A | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
SNP | Allele | Asthma | Atopy | Atopic asthma | ||||||
S:E(S) | Z | p | S:E(S) | Z | p | S:E(S) | Z | p | ||
rs3126085 | A | 32.0:50.2 | -3.48 | 0.0005 | 35.0:49.8 | -2.94 | 0.0033 | 25.0:37.2 | -2.74 | 0.0061 |
G | 148.0:129.8 | 3.48 | 141.0:126.2 | 2.94 | 109.0:96.8 | 2.74 | ||||
B | ||||||||||
SNP/Haplotype | Allele | Asthma and AD | Atopy and AD | Atopic asthma and AD | ||||||
S:E(S) | Z | p | S:E(S) | Z | P | S:E(S) | Z | p | ||
rs3126085 | A | 14.0:24.0 | -2.94 | 0.0033 | 16.0:24.5 | -2.59 | 0.0097 | 10.0:18.0 | -2.74 | 0.0062 |
G | 66.0:56.0 | 2.94 | 62.0:53.5 | 2.59 | 52.0:44.0 | 2.74 | ||||
H1 | T G | 75.0:66.0 | 2.61 | 0.009 | 75.0:64.0 | 3.33 | 0.0009 | 60.0:51.0 | 2.94 | 0.0033 |