Table 1 Risk of peanut allergy vs. shellfish allergy in association with Rh immune globulin and folic acid exposure in pregnancy, as well as reduced intake of peanut containing products in pregnancy
| Â | Â | No. (%) with self-reported exposure | Â | |
|---|---|---|---|---|
Maternal exposure in index pregnancy | Among mothers of cases with a peanut allergy | Among mothers of controls with a shellfish allergy | Odds ratio (95% CI), cases vs. controls | |
Received Rh immune globulin | No (n = 1027) | 961 (73.2) | 66 (61.7) | 1.00 (ref) |
| Â | Yes (n = 271) | 251 (19.1) | 20 (18.7) | 0.86 (0.51 to 1.45) |
| Â | Unknown (n = 121) | 100 (7.6) | 21 (19.6) | -- |
Initiated a folic acid supplement before conception | No (n = 560) | 508 (38.7) | 52 (48.6) | 1.00 (ref) |
| Â | Yes (n = 817) | 764 (58.2) | 53 (49.5) | 1.48 (0.99 to 2.20) |
| Â | Unknown (n = 42) | 40 (3.1) | 2 (1.9) | -- |
Initiated a folic acid supplement after conception | No (n = 53) | 49 (9.0) | 4 (7.3) | 1.00 (ref) |
| Â | Yes (n = 536) | 485 (88.7) | 51 (92.7) | 0.78 (0.27 to 2.24) |
| Â | Unknown (n = 13) | 13 (2.4) | 0 (0.0) | -- |
Took a folic acid supplement throughout pregnancy | No (n = 91) | 87 (7.1) | 4 (3.9) | 1.00 (ref) |
| Â | Yes (n = 1232) | 1134 (92.2) | 98 (95.2) | 0.53 (0.19 to 1.48) |
| Â | Unknown (n = 10) | 9 (0.73) | 1 (0.97) | -- |
Reduced intake of peanut-containing products in pregnancy | None (n = 1095) | 1013 (77.6) | 82 (76.6) | 1.00 (ref) |
| Â | Somewhat (n = 236) | 222 (17.0) | 14 (13.1) | 1.28 (0.72 to 2.30) |
| Â | Completely (n = 82) | 71 (5.4) | 11 (10.3) | 0.53 (0.27 to 1.03) |
| Â | Unknown (n = 58) | 52 (3.8) | 6 (5.3) | -- |