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Table 2 Comparisons of T-cell expression in spleen cells among three mice groups

From: VIP Regulates the Development & Proliferation of Treg in vivo in spleen

 

Group 1: Controls

(n = 10)

Group 2: VIP KO

(n = 5)

Group 3: VIP KO + VIP

(n = 5)

p-values

for Group Comparisons

 

Median

Min, Max

Median

Min, Max

Median

Min, Max

1 vs. 2

1 vs. 3

2 vs. 3

CD4-CD25+

29

6, 73

31

19, 429

47

33, 89

0.63

0.12

0.18

CD4-CD25+Helios+

1

0, 4

4

0, 164

2

0, 10

0.046

0.31

0.61

CD4-CD25+FoxP3+Helios+

4

0, 19

0

0, 0

0

0, 2

0.069

0.32

0.14

CD4+CD25+

(Treg)

435

88, 1383

374

199, 611

380

198, 489

1.00

1.00

0.61

CD4+CD25+FoxP3+Helios-

(Treg induced intrasplenically)

109

8, 359

9

4, 37

150

99, 226

0.038

0.91

0.0091*

CD4+CD25+FoxP3-Helios+

(Treg)

83

0, 270

254

108, 352

96

21, 157

0.028

0.91

0.029

CD4+CD25+ FoxP3+Helios+

(Treg)

68

2, 251

6

0, 22

82

53, 141

0.087

0.91

0.0091*

  1. Note: p-values were based on Mann-Whitney tests; *: statistically significant at adjusted alpha = 0.017.