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Table 2 Inflammatory parameters following nasal control challenge, and 1 and 4 days of nasal allergen challenges

From: Comparative responses to nasal allergen challenge in allergic rhinitic subjects with or without asthma

Parameter

Rhinitics

Asthmatics

 

Control

Day 1

Day 4

Control

Day 1

Day 4

Nasal lavage eosinophils (%)

1.3 ± 0.9

3.0 ± 1.3

15.5 ± 9.6 *

2.1 ± 0.6

7.5 ± 4.3

15.7 ± 5.4*

Nasal lavage ECP (ng/mL)

3.8 ± 1.5

8.7 ± 3.4 *

7.9 ± 2.6

8.6 ± 3.2

10.3 ± 2.7 *

9.4 ± 4.0

Induced sputum eosinophils (%)

2.0 ± 1.3

1.3 ± 1.5

1.6 ± 1.0

5.6 ± 1.8

6.0 ± 1.7

4.1 ± 1.4

Induced sputum ECP (ng/mL)

72 ± 20

112 ± 41

98 ± 36

146 ± 43

171 ± 41

242 ± 106

  1. Data are presented as mean ± SEM
  2. * p < 0.05 vs control challenge