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Table 4 Overview of the defining features of innate and adaptive immunity [1].

From: An introduction to immunology and immunopathology

 

Innate immune system

Adaptive immune system

Cells

Hematopoietic cells:

• macrophages

• dendritic cells

• mast cells

• neutrophils

• basophils

• eosinophils

• NK cells

• T cells

• non-hematopoietic cells

• epithelial cells (skin, airways, gastrointestinal tract)

Hematopoietic cells:

• T cells

• B cells

Molecules

cytokines

• complement

• proteins and glycoprotein

antibodies (Ig)

• cytokines

Response time

immediate

delayed by hours to days

Immunologic memory

none: responses are the same with each exposure

responsiveness enhanced by repeated antigen exposure