Table 3 Clinical criteria for diagnosing anaphylaxis [1, 2]
From: Anaphylaxis
Anaphylaxis is highly likely when any 1 of the following 3 criteria is fulfilled following exposure to an allergen: | |
|---|---|
1 | Acute onset of an illness (minutes to several hours) with involvement of the skin, mucosal tissue, or both (e.g., generalized hives, pruritus or flushing, swollen lips-tongue-uvula) and at least 1 of the following: a. Respiratory compromise (e.g. dyspnea, wheeze, bronchospasm, stridor, reduced PEF, hypoxemia) b. Reduced BP or associated symptoms of end-organ dysfunction (e.g. hypotonia [collapse], syncope, incontinence) |
2 | 2 or more of the following that occur rapidly after exposure to a likely allergen for that patient (minutes to several hours): a. Involvement of the skin-mucosal tissue (e.g., generalized hives, itch-flush, swollen lips-tongue-uvula) b. Respiratory compromise (e.g., dyspnea, wheeze, bronchospasm, stridor, reduced PEF, hypoxemia) c. Reduced BP or associated symptoms (e.g., hypotonia [collapse], syncope, incontinence) d. Persistent GI symptoms (e.g., painful abdominal cramps, vomiting) |
3 | Reduced BP after exposure to a known allergen for that patient (minutes to several hours): a. Infants and children: low systolic BP (age specific) or > 30% decrease in systolic BP* b. Adults: systolic BP < 90 mmHg or > 30% decrease from that person’s baseline |