From: Urticaria and angioedema
 | Usual adult dose | Usual pediatric dose |
---|---|---|
Second-generation H1-receptor antihistamines (first-line therapy) | ||
Cetirizine (Reactine) | 10-40 mg daily | 5-10 mL (1-2 teaspoons) daily (children’s formulation) |
Desloratadine (Aerius) | 5-20 mg daily | 2.5-5 mL (0.5-1.0 teaspoon) daily (children’s formulation) |
Fexofenadine (Allegra) | 120-480 mg daily | Not currently indicated for children under 12 years of age |
Loratadine (Claritin) | 10-40 mg daily | 5-10 mL (1-2 teaspoons) daily (children’s formulation) |
First-generation H1-receptor antihistamines (best used as adjunctive therapy for patients with nocturnal symptoms) | ||
Hydroxyzine (Atarax) | 25-50 mg, three to four times daily | Children < 6 years: 30 to 100 mg daily in divided doses |
Diphenhydramine (Benadryl) | 25-50 mg, every -6 hours | 2.5-20 mL (0.5-4 teaspoons) every 4 to 6 hours (depending on age/weight) |
Cyproheptadine (Periactin) | 4-20 mg daily | 2-4 mg, two to three times daily (depending on age/weight) |
Chlorpheniramine (Chor-Tripolon) | 4 mg every 4–6 hours | 1 mg every 4–6 hours |
Clemastine (Tavist-1) | 1.34 - 2.68 mg, two to three times daily | 1.34 mg, once or twice daily |