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Table 3 Comparison of HAE and AAE.

From: Urticaria and angioedema

  Age of onset Family history Complement levels
    C1q C4 C1 inh level C1 inh function
HAE
Type 1
Type 2 		Early Yes* Normal
Normal 		Low
Low 		Low
Normal/elevated 		Low
Low
AAE Late No Low Low Normal or low Low
  1. *In approximately 25% of patients, no family history is identified; the disorder results from spontaneous mutation of the C1 inhibitor gene.
  2. C1 inh: C1 inhibitor
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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