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Table 3 Comparison of HAE and AAE.

From: Urticaria and angioedema

 

Age of onset

Family history

Complement levels

   

C1q

C4

C1 inh level

C1 inh function

HAE

Type 1

Type 2

Early

Yes*

Normal

Normal

Low

Low

Low

Normal/elevated

Low

Low

AAE

Late

No

Low

Low

Normal or low

Low

  1. *In approximately 25% of patients, no family history is identified; the disorder results from spontaneous mutation of the C1 inhibitor gene.
  2. C1 inh: C1 inhibitor
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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