From: How do questionnaire definitions of atopy status affect sample size calculations for asthma cohort studies in a population of Canadian children?
Number of atopic conditions
Sensitivity
Specificity
Youden’s index
PPV
NPV
Sample size for nested cohort study
1
54.3%
65.8%
20.1%
72.6%
46.3%
344
2
24.4%
98.7%
23.1%
96.9%
44.8%
2948
3
4.7%
100.0%
39.3%
21034