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Table 1 Sensitivity, specificity, PPV and NPV of questionnaire-based definitions of atopy compared to the gold standard of SPT and sample size calculations for a nested cohort study

From: How do questionnaire definitions of atopy status affect sample size calculations for asthma cohort studies in a population of Canadian children?

Number of atopic conditions

Sensitivity

Specificity

Youden’s index

PPV

NPV

Sample size for nested cohort study

1

54.3%

65.8%

20.1%

72.6%

46.3%

344

2

24.4%

98.7%

23.1%

96.9%

44.8%

2948

3

4.7%

100.0%

4.7%

100.0%

39.3%

21034