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Table 1

From: Use of Omalizumab to treat a nine-year old, with steroid-dependent, allergic asthma, adrenal insufficiency and vertebral compression fractures due to steroid induced severe osteoporosis

 

Daily Prednisone

Daily ICS dose

FEV1

Serum cortisol‡

Bone density*

PAQLQ†

2010a

30 mg

800 mcg

1.46 L

12 nmol/L

0.626 g/cm2

4.7

2011 b

NIL

200 mcg

1.98 L

215 nmol/L

0.686 g/cm2

7

  1. a Pre Omalizumab treatment
  2. b Post Omalizumab treatment
  3. ‡Morning results, range 185 – 624 nmol/L
  4. *Total hip
  5. †Pediatric asthma quality of life questionnaire with standardized activities: low 1 – 7 high