Figure 4

Results of BAT (left) and FEIA (right) in atopic patients (n = 39, squares and asterisks) and non-atopic persons (n = 28, diamonds). The atopic patients are divided into those allergic to the allergen of interest per SPT result ("Atopic SPT^pos", squares) and those allergic to a different allergen(s) ("Atopic SPT^neg", asterisks). The numbers of Atopic SPT+ patients were 19 for cat, 14 for dog, 11 for D.pteronyssimus, 26 for Timothy, and 21 for birch. The numbers of Atopic SPT^neg patients can be calculated for each allergen as 39 minus the number of Atopic SPT^pos patients (eg, 39-19 = 20 for cat). Significance of the difference between the Atopic SPT^pos and Atopic SPT^neg groups and between Atopic SPT^neg and Non-atopic groups is given in the upper section of each plot. BAT results are displayed as corrected percentage of activated (CD63+) basophils (saline control percentage subtracted). Undetectable IgE levels by FEIA are displayed as 0.05 kU/L. Dashed lines denote cutoffs for positivity. Cutoff for FEIA positivity was 0.1 kU/L, while that for BAT varied for different allergens - 15% above background for Cat and Timothy, 25% for DP and 30% for Dog and Birch.