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Table 3 Clinical and genetic features of the 11 Algerian patients with MHC class II deficiency

From: Clinical, immunological and genetic features in eleven Algerian patients with major histocompatibility complex class II expression deficiency

Patients Sex Age at diagnosis Consanguinity Death in siblings (with similar symptoms) Morbidities I5E6-25_I5E6+1 mutation
1 F 10 y + None Chronic diarrhoea, respiratory tract infections +
2 M 2 y 6 m + None Chronic diarrhoea +
3 M 4 y + 2 brothers Chronic diarrhoea, thrush +
4 F 2 m + 2 brothers None +
5 F 1 y 10 m + 1brother, 1 sister Chronic diarrhoea, thrush +
6 M 4 y + None Chronic diarrhoea, respiratory tract infections +
7 M 2 y 3 m + None Chronic diarrhoea, respiratory tract infections
8 F 4 y None Chronic diarrhoea, respiratory tract infections, molluscum contagiosum +
9 M 1 y 10 m None Chronic diarrhoea, respiratory tract infections, abcess, eczema, thrush, genito-urinary tract infections
10 M 6 y None Respiratory tract infections +
11 F 4 y + None Chronic diarrhoea, respiratory tract infections +