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Table 4 Associations between circulating exposures to wheeze inducing pathogens, and risk of hospital admission for asthma by 12-months

From: Pollen exposure in pregnancy and infancy and risk of asthma hospitalisation - a register based cohort study

 

Crude OR

Mutually adjusted

Model 1*

Model 2†

Model 3‡

Effect per inter-quartile range increase**

   

First 3- months

1.15 (1.07-1.23)

1.16 (1.08-1.25)

1.04 (0.93-1.17)

1.05 (0.92-1.20)

1.04 (0.91-1.17)

3-6 months

1.17 (1.09-1.26)

1.19 (1.10-1.27)

1.07 (0.95-1.20)

1.06 (0.93-1.20)

0.98 (0.86-1.12)

Highest 25% of children exposed

    

First 3- months

1.19 (1.04-1.38)

1.23 (1.06-1.42)

1.06 (0.88-1.27)

1.07 (0.88-1.30)

1.07 (0.89-1.29)

3-6 months

1.16 (1.00-1.34)

1.19 (1.03-1.38)

0.99 (0.81-1.20)

0.96 (0.78-1.17)

0.98 (0.80-1.18)

  1. * Model 1. Adjusted for year and season of birth, maternal smoking, infant gender and gestational age.
  2. ** Per inter-quartile range increase in hospital admissions for LRTI (18.7 admissions per week for both time periods).
  3. Model 2. As per model 1, and also adjusted for averaged concentration levels of airborne pollutants (O3 & NO2) during the first and third trimester and during the first three months of infancy.
  4. Model 3. As per model 1, and also adjusted for period prevelences of pollen exposure in the first and third trimester, and the first three months of infancy.