Table 3 Published cases of immediate-type hypersensitivity reactions to heparins
From: Allergic anaphylaxis due to subcutaneously injected heparin
No. | Age (years) | Sex | Causative heparin | Clinical symptoms | Skin test (causative heparin) | BAT (causative heparin) | Ref. |
|---|---|---|---|---|---|---|---|
1 | 36 | m | Porcine heparin | Blood pressure decrease, airway stoppage, heart fibrillation | SPT (titrated) positive | n.d. | [9] |
2 | 30 | f | Dalteparin | Urticaria, nausea, dyspnea, swollen hands | SPT positive IDT (1:100) positive | n.d. | [6] |
3 | 52 | m | Heparin | Hypotension, tachycardia, loss of consciousness | SPT negative IDT (undiluted) positive | n.d. | [8] |
4 | 42 | f | Nadroparin | Generalised urticaria, angioedema, hypotension, collapse | SPT positive | n.d. | [7] |
5 | 18 | f | Enoxaparin | Erythematous infiltrated plaques, angioedema | SPT negative, IDT (diluted?) positive | positive | [5] |
6 | 27 | f | Enoxaparin | Erythematous infiltrated plaques, angioedema, dizziness, sweating | SPT negative, IDT negative | negative | [5] |
7 | 59 | f | Dalteparin | Blood pressure decrease, frequent arrhythmias, dyspnea | n.d. | negative | [11] |
8 | 52 | f | Reviparin | Dyspnea, cough, wheezing | n.d. | n.d. | [12] |
9 | 67 | f | Heparin | Cardiac and respiratory arrest | n.d. | n.d. | [13] |