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Table 1 Quality scoring based on the Newcastle-Ottawa quality assessment scale: cohort studies

From: A systematic review of CD14 and toll-like receptors in relation to asthma in Caucasian children

First author Year S1 S2 S3 S4 C1a C1b O1 O2 O3 OQ
Bieli † [10] 2007 * * * - * * - * - +/−
Bottema [26] 2010 * * NA * - - - * - +/−
Custovic [62] 2011 * * - * * * - * * +
Eder † [25] 2004 * * * - * * - * - +/−
Ege † [22] 2007 * * * - * * - * - +/−
Fageras Bottcher † [39] 2004 - * * - * * * * - +/−
Guerra [11] 2004 * * - * * * - - - +/−
Jones [48] 2002 - * NA * - - - - -
Kabesch † [13] 2004 * * NA * - - - * - +/−
Kerkhof [56] 2010 * * * * * * - * - +
Lange [63] 2011 * * NA - * * * * - +
Lodrup Carlsen [51] 2010 * * NA * * * - * * +
O’Donnell [36] 2004 * * NA - * * - * * +
Reijmerink [41] 2010 * * NA * - - - * - +/−
Rothenbacher [53] 2005 * * * * * * - - * +
Simpson [8] 2006 * * * * * * - * * +
Snijders † [52] 2006 * * * * * * - - * +
Soferman [54] 2004 - * NA * * * * * * +
  1. S1: Representativeness of the exposed cohort, S2: Selection of non-exposed cohort, S3: Ascertainment of exposure, S4: Outcome of interest not present at start of study, C1a/C1b: Comparability of cohorts on the basis of the design or analysis, O1: Assessment of outcome, O2: Duration of follow-up, O3: Adequacy of follow up (*: criteria were met; -: criteria were not met); OQ: Overall quality (+ better than average quality, +/− average quality, – less than average quality); NA = not applicable; † cross-sectional study.
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