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Table 1 Restricted medications and required washout times

From: A four-way, double-blind, randomized, placebo controlled study to determine the efficacy and speed of azelastine nasal spray, versus loratadine, and cetirizine in adult subjects with allergen-induced seasonal allergic rhinitis

Prohibited medication

Time frame prohibited prior to first priming visit and thereafter

Decongestants

Within 48 hours

Topical glucocorticoids

Within 14 days

Tricyclic antidepressants

Within 14 days

Tranquilizers

Within 14 days

Monoamine oxidase inhibitors

Within 14 days

Long acting β-2 agonists

Within 14 days

Glucocorticoids (inhaled, oral or intravenous)

Within 28 days

Glucocorticoids (intramuscular or intra-articular)

Within 84 days

Antihistamines

Within 7 days

Leukotrienes antagonists

Within 7 days

Theophylline

Within 7 days

Non-steroidal anti-inflammatory drugs

Within 7 days

Systemic antibodies

Within 7 days