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Table 1 Restricted medications and required washout times

From: A four-way, double-blind, randomized, placebo controlled study to determine the efficacy and speed of azelastine nasal spray, versus loratadine, and cetirizine in adult subjects with allergen-induced seasonal allergic rhinitis

Prohibited medication Time frame prohibited prior to first priming visit and thereafter
Decongestants Within 48 hours
Topical glucocorticoids Within 14 days
Tricyclic antidepressants Within 14 days
Tranquilizers Within 14 days
Monoamine oxidase inhibitors Within 14 days
Long acting β-2 agonists Within 14 days
Glucocorticoids (inhaled, oral or intravenous) Within 28 days
Glucocorticoids (intramuscular or intra-articular) Within 84 days
Antihistamines Within 7 days
Leukotrienes antagonists Within 7 days
Theophylline Within 7 days
Non-steroidal anti-inflammatory drugs Within 7 days
Systemic antibodies Within 7 days