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Table 4 Participant ratings of overall effectiveness of the medication

From: A four-way, double-blind, randomized, placebo controlled study to determine the efficacy and speed of azelastine nasal spray, versus loratadine, and cetirizine in adult subjects with allergen-induced seasonal allergic rhinitis

 

Placebo

Cetirizine

Loratadine

Azelastine

 

(N = 66)

(N = 66)

(N = 66)

(N = 66)

Very good

6 (9%)

14 (21%)

8 (12%)

11 (17%)

Good

6 (9%)

20 (30%)

12 (18%)

19 (29%)

Satisfactory

10 (15%)

20 (30%)

22 (33%)

21 (32%)

Insufficient

44 (67%)

12 (18%)

24 (36%)

15 (23%)

Mean

3.4

2.5

2.9

2.6

Std.

0.99

1.03

1.02

1.02

Median

4.0

2.0

3.0

3.0

Min. to Max.

1-4

1-4

1-4

1-4

P value vs. placebo

 

<0.001

0.003

<0.001

  1. P-values and estimates obtained from a mixed effects cumulative logit proportional odds model with fixed effects for sequence, period, and treatment and random effects for subject within sequence.