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Table 1 Clinical features suggestive of Immunodeficiency[6]

From: Spectrum of primary immunodeficiency disorders in Sri Lanka

History Number (%)
(n = 942)
Age
Birth - < 1 year 362 (38.4)
1 - < 5 years 359 (38.15)
5 - < 12 years 49 (5.2)
12- < 18 years 41 (4.35)
18- < 30 years 49 (5.2)
> 30 years 82 (8.7)
Sex
Male 526 (55.8)
Female 416 (44.16)
Recurrent (proven) infection
≥ 2 severe infections (pneumonia, sepsis, meningitis, osteomyelitis) 393 (42.7)
Atypical presentation of infection 6 (0.6)
Unusually severe course, or impaired response to treatment 230 (24.4)
Unusual or opportunistic agent 10 (1.0)
Recurrent infections with same type of pathogen 60 (6.3)
Abscesses of internal organs, or recurrent subcutaneous abscesses 115 (12.2)
FTT with prolonged/recurrent diarrhoea 24 (2.5)
Generalized long lasting warts or molluscum contagiosum 5 (0.5)
Extensive prolonged candidiasis 16 (1.7)
Delayed separation (> 4 weeks) of umbilical cord 2 (0.2)
Delayed shedding of primary teeth 2 (0.2)
F/H of infant deaths, ID, consanguinity 16 (1.7)
Difficult to treat obstructive lung disease, unexplained bronchiectasis 50 (5.3)
Physical examination
Dysmorphic features, especially facial abnormalities, microcephaly 0
Partial albinism, abnormal hair, severe eczema 3 (0.3)
Telangiectasia, ataxia 10 (1.0)
Gingivitis, oral ulcers/aphthae 0
Absence of immunological tissue 0
Organomegaly 0
Digital clubbing 0