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Table 1 Total Nasal Symptom Scores (TNSS) Each symptom (sneezing, congestion, itching, and rhinorrhea) is graded from 0-3 by the participants during the screening and NAC visits

From: The Allergic Rhinitis – Clinical Investigator Collaborative (AR-CIC): nasal allergen challenge protocol optimization for studying AR pathophysiology and evaluating novel therapies

Score Symptoms
0=None No symptoms evident
1=Mild Symptom present but easily tolerated
2=Moderate Definite awareness of symptom; bothersome but tolerable
3=Severe Symptom hard to tolerate; interferes with daily activity
  1. The Nasal symptoms are then added for each time points to reach the TNSS.