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Table 1 Total Nasal Symptom Scores (TNSS) Each symptom (sneezing, congestion, itching, and rhinorrhea) is graded from 0-3 by the participants during the screening and NAC visits

From: The Allergic Rhinitis – Clinical Investigator Collaborative (AR-CIC): nasal allergen challenge protocol optimization for studying AR pathophysiology and evaluating novel therapies

Score

Symptoms

0=None

No symptoms evident

1=Mild

Symptom present but easily tolerated

2=Moderate

Definite awareness of symptom; bothersome but tolerable

3=Severe

Symptom hard to tolerate; interferes with daily activity

  1. The Nasal symptoms are then added for each time points to reach the TNSS.