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Table 2 Patients diagnosed with penicillin allergy pre-challenge

From: A retrospective comparison of false negative skin test rates in penicillin allergy, using pencilloyl-poly-lysine and minor determinants or Penicillin G, followed by open challenge

A. Positive skin tests

Patient

Age

Sex

Reaction

Skin prick test

Intradermal

Immunocap

Challenge

+

+

PenG

PenV

1

17

F

Previous positive skin test, reaction unknown

 

PPL, MDM

PPL

MDM

ND

ND

ND

2

44

F

Rash

 

PPL, MDM

MDM

PPL

ND

3

49

M

Delayed hives

 

PPL, MDM

PPL

MDM

ND

4

29

M

Facial swelling

 

PPL, MDM, AMP

MDM, AMP

PPL

+

5

25

F

Unknown

 

PPL, MDM

PPL

MDM

ND

6

46

M

Unknown

n/d

n/d

PPL

MDM

ND

7

78

F

Delayed prolonged rash

MDM

PPL, CLX

 

MDM, PPL, CLX

ND

8

53

F

Facial swelling

  

PPL, MDM, AMP

 

ND

9

71

F

Oral tingling

 

PPL, PG, AMP

PPL, AMP

PG

10

41

F

Anaphylaxis

 

PPL

PG

CLX, ANF

ND

11

72

F

Delayed rash

  

PPL (delayed)

PG

+

ND

12

29

M

Not known

PG

   

ND

13

56

F

Rash

  

AMP (delayed)

PPL, PG

14

60

M

Rash

  

PPL, PG

CFZ

ND

15

19

F

Delayed rash

PG

PPL, AMP

  

ND

16

46

F

Rash

AMP

PPL, PG

  

ND

17

40

F

Hives, throat tightness

  

PG, AMP

PPL

ND

B. Positive specific IgE to Penicillin G or V by ImmunCap®

Patient

Age

Sex

Reaction

Skin testing negative to

Immunocap

PenG

PenV

1

43

F

Erythema, pruritus

PPL, PG

+

2

25

F

Rash

PPL, PG

+

3

77

F

Rash, face/lip swelling

PPL, PG

+

  1. A Positive skin test, B positive specific IgE (if negative skin testing)
  2. PPL benzyl penicilloyl-polylysine, MDM minor determinant mixture, PG Penicillin G, ND not done, AMP ampicillin, CLX Cloxacillin, CFZ ceftazidime, ANF cefazolin