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Table 1 Comparison of ROC analysis results for methods of identification of type I hypersensitivity using allergen extracts, recombinant components, and recombinant components groups

From: Allergen extracts and recombinant proteins: comparison of efficiency of in vitro allergy diagnostics using multiplex assay on a biological microchip

Antigen

AUC

P value

Birch pollen (Positive: 56, Negative: 36)

 Natural extract of birch pollen

0.95

<0.0001

 Bet v 1

0.95

<0.0001

 Bet v 2

0.83

<0.0001

 Bet v 1 + Bet v 2a

0.95

<0.0001

Cat dander (Positive: 73, Negative: 66)

 Natural extract of cat dander

0.76

<0.0001

 Fel d 1

0.76

<0.0001

Timothy grass pollen (Positive: 33, Negative: 59)

 Natural extract of timothy grass pollen

0.83

<0.0001

 Phl p 1

0.71

<0.001

 Phl p 5

0.65

<0.02

 Phl p 7

0.65

<0.02

 Phl p 12

0.66

<0.01

 Phl p 1 + Phl p 5

0.71

<0.001

 Phl p 1 + Phl p 5 + Phl p 7 + Phl p 12a

0.74

<0.0001

  1. aFor the recombinant proteins groups the sample was considered positive if at least one of the proteins showed positive result for the current cut-off