Skip to main content

Advertisement

Table 1 Comparison of ROC analysis results for methods of identification of type I hypersensitivity using allergen extracts, recombinant components, and recombinant components groups

From: Allergen extracts and recombinant proteins: comparison of efficiency of in vitro allergy diagnostics using multiplex assay on a biological microchip

Antigen AUC P value
Birch pollen (Positive: 56, Negative: 36)
 Natural extract of birch pollen 0.95 <0.0001
 Bet v 1 0.95 <0.0001
 Bet v 2 0.83 <0.0001
 Bet v 1 + Bet v 2a 0.95 <0.0001
Cat dander (Positive: 73, Negative: 66)
 Natural extract of cat dander 0.76 <0.0001
 Fel d 1 0.76 <0.0001
Timothy grass pollen (Positive: 33, Negative: 59)
 Natural extract of timothy grass pollen 0.83 <0.0001
 Phl p 1 0.71 <0.001
 Phl p 5 0.65 <0.02
 Phl p 7 0.65 <0.02
 Phl p 12 0.66 <0.01
 Phl p 1 + Phl p 5 0.71 <0.001
 Phl p 1 + Phl p 5 + Phl p 7 + Phl p 12a 0.74 <0.0001
  1. aFor the recombinant proteins groups the sample was considered positive if at least one of the proteins showed positive result for the current cut-off