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Table 2 Comparing the percentages and absolute numbers of regulatory B cells in the airways of allergic asthmatics, allergic non-asthmatics and healthy controls

From: Proceedings of the Canadian society of allergy and clinical immunology annual scientific meeting 2015

Subset of cells in sputum

Asthmatics (n = 12)

Allergic non-asthmatics (n = 8)

Healthy controls (n = 7)

SSClowCD45+/CD45+ (%)

1.5 ± 0.3*

2.8 ± 0.3

2.3 ± 0.5

CD19+/SSClowCD45+ (%)

13.4 ± 2.0*

6.6 ± 1.5

4.4 ± 1.0

CD19+/CD45 + (%)

0.19 ± 0.04

0.19 ± 0.05

0.08 ± 0.01

CD19+ (×106 cells/g of sputum)

0.007 ± 0.002

0.011 ± 0.004

0.002 ± 0.0009

CD19+FoxP3+/SSClowCD45+ (%)

1.8 ± 0.5

0.6 ± 0.2

0.6 ± 0.3

CD19+FoxP3+/CD45+ (%)

0.02 ± 0.007

0.02 ± 0.004

0.01 ± 0.008

CD19+FoxP3+ (×106 cells/g of sputum) (%)

0.0006 ± 0.0001

0.0007 ± 0.0001

0.0006 ± 0.0004

CD19+FoxP3+CD5+/SSClowCD45+ (%)

1.0 ± 0.3

0.4 ± 0.2

0.3 ± 0.1

CD19+FoxP3+CD5+/CD45+ (%)

0.016 ± 0.009

0.010 ± 0.004

0.005 ± 0.002

CD19+FoxP3+CD5+ (×106 cells/g of sputum)

0.0004 ± 0.00018

0.0005 ± 0.00017

0.0002 ± 0.00009

CD19+FoxP3+IL-10+/SSClowCD45+ (%)

0.35 ± 0.10

0.16 ± 0.07

0.05 ± 0.02

CD19+FoxP3+IL-10+/CD45+ (%)

0.005 ± 0.0023

0.004 ± 0.0019

0.001 ± 0.0006

CD19+FoxP3+IL-10+ (×106 cells/g of sputum)

0.00013 ± 0.00005

0.00018 ± 0.00007

0.00004 ± 0.00003

  1. * p < 0.05 compared across subject groups