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Table 3 Comparing the percentages and absolute numbers of IgE-expressing B cells in the airways and blood of allergic asthmatics, allergic non-asthmatics and healthy controls

From: Proceedings of the Canadian society of allergy and clinical immunology annual scientific meeting 2015

Subset of cells

Asthmatics blood (n = 11)

Allergic non-asthmatics blood (n = 11)

Healthy controls blood (n = 7)

SSClowCD45+/CD45+ cells (%)

46.2 ± 3.9

38.3 ± 4.6

50.5 ± 5.1

CD19+/SSClowCD45+ (%)

11.4 ± 1.0

13.2 ± 0.9

8.6 ± 1.3

CD19+/CD45+ (%)

6.0 ± 0.5

4.4 ± 0.6

4.4 ± 0.8

CD19+ (×106 cells/mL of blood)

0.38 ± 0.07

0.26 ± 0.04

0.31 ± 0.06

CD19+IgE+/SSClowCD45+ (%)

0.24 ± 0.05

0.13 ± 0.03

0.27 ± 0.15

CD19+IgE+/CD45+ (%)

0.15 ± 0.04

0.06 ± 0.02

0.12 ± 0.06

CD19+IgE+ (×106 cells/mL of blood)

0.010 ± 0.004

0.004 ± 0.001

0.007 ± 0.003

Subset of cells

Asthmatics sputum (n = 10)

Allergic non-asthmatics sputum (n = 7)

Healthy controls sputum (n = 6)

SSClowCD45 +/CD45+ (%)

1.6 ± 0.4

2.0 ± 0.8

1.9 ± 0.4

CD19+/SSClowCD4+ (%)

11.8 ± 2.0*

5.7 ± 1.0

4.6 ± 0.6

CD19+/CD45+ (%)

0.18 ± 0.04

0.11 ± 0.03

0.08 ± 0.02

CD19+ (×106 cells/g of sputum)

0.008 ± 0.002

0.005 ± 0.003

0.002 ± 0.0003

CD19+IgE+/SSClowCD45+ (%)

3.5 ± 1.0*

0.4 ± 0.1

0.2 ± 0.1

CD19+IgE+/CD45+ (%)

0.048 ± 0.011*

0.007 ± 0.002

0.004 ± 0.002

CD19+IgE+ (×106 cells/g of sputum

0.0020 ± 0.00063*

0.0003 ± 0.00009

0.0001 ± 0.00004

  1. * p < 0.05 compared across subject groups