Cytokine patterns in nasal secretion of non-atopic patients distinguish between chronic rhinosinusitis with or without nasal polys

Table 1 Cytokine levels in nasal fluid in healthy controls, NP and CRSsNP participants

	IL-4	IL-5	IL-8	IL-13	Eotaxin	GM-CSF	RANTES	MCP-1	MIP-1α
Controls	7 0–32	5 1–238	1310 189–42,868	19 10–32	45 0–154	32 0–137	9 0–259	66 17–401	0 0–113
NP	7 0–17	10 0–500	1851 0–265,037	10 4–62	75 0–422	27 0–112	14 0–563	117 13–3867	6 0–60
CRSsNP	5 0–30	3 1–1831	1877 0–1,384,113	15 2–92	49 0–339	42 0–132	35 0–426	89 0–1676	0 0–673
P values
NP—Con	n.s. (0.822)	n.s. (0.070)	n.s. (0.562)	s. (< 0.001)	n.s. (0.114)	n.s. (0.286)	n.s. (0.447)	s. (< 0.001)	s. (< 0.001)
CRSsNP—Con	n.s. (0.133)	n.s. (0.025)*	n.s. (0.291)	s. (< 0.01)	n.s. (0.361)	n.s. (0.456)	s. (< 0.050)	n.s. (0.028)*	n.s. (0.028)*
NP—CRSsNP	n.s. (0.213)	s. (<0.001)	n.s. (0.887)	s. (< 0.01)	n.s. (0.315)	n.s. (0.148)	n.s. (0.079)	n.s. (0.024)*	n.s. (0.037)*

Concentrations are given in pg/ml. Data are presented as median (upper line) and range (lower line). To control the false discovery rate, we used the method of Benjamini and Yukatieli. Thus, values marked with ‘*’ are regarded as non-significant despite p < 0.05
n.s. not significant; s. significant

ISSN: 1710-1492