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Table 1 Cytokine levels in nasal fluid in healthy controls, NP and CRSsNP participants

From: Cytokine patterns in nasal secretion of non-atopic patients distinguish between chronic rhinosinusitis with or without nasal polys

  IL-4 IL-5 IL-8 IL-13 Eotaxin GM-CSF RANTES MCP-1 MIP-1α
Controls 7
0–32
5
1–238
1310
189–42,868
19
10–32
45
0–154
32
0–137
9
0–259
66
17–401
0
0–113
NP 7
0–17
10
0–500
1851
0–265,037
10
4–62
75
0–422
27
0–112
14
0–563
117
13–3867
6
0–60
CRSsNP 5
0–30
3
1–1831
1877
0–1,384,113
15
2–92
49
0–339
42
0–132
35
0–426
89
0–1676
0
0–673
P values
 NP—Con n.s. (0.822) n.s. (0.070) n.s. (0.562) s. (< 0.001) n.s. (0.114) n.s. (0.286) n.s. (0.447) s. (< 0.001) s. (< 0.001)
 CRSsNP—Con n.s. (0.133) n.s. (0.025)* n.s. (0.291) s. (< 0.01) n.s. (0.361) n.s. (0.456) s. (< 0.050) n.s. (0.028)* n.s. (0.028)*
 NP—CRSsNP n.s. (0.213) s. (<0.001) n.s. (0.887) s. (< 0.01) n.s. (0.315) n.s. (0.148) n.s. (0.079) n.s. (0.024)* n.s. (0.037)*
  1. Concentrations are given in pg/ml. Data are presented as median (upper line) and range (lower line). To control the false discovery rate, we used the method of Benjamini and Yukatieli. Thus, values marked with ‘*’ are regarded as non-significant despite p < 0.05
  2. n.s. not significant; s. significant
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