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Table 1 Characteristics of studies reporting primary outcome (skin prick testing)

From: Diagnostic accuracy of skin-prick testing for allergic rhinitis: a systematic review and meta-analysis

Study, year Country Setting Sample size No. of males (%) Mean age (range), years Nasal provocation positive Nasal provocation negative Wheal size cut-off (mms) Sensitivity, % Specificity, % Allergen extracts
Zarei et al. [25] USA Clinic 45 21 (47) 39 (25–66) 18 27 ≥3a 100.0 74.1 Cat
Krouse et al. [14] USA Hospital 37 NR NR (18–70) 15 22 ≥3a 87.0 86.0 Timothy grass
Krouse et al. [14] USA Hospital 44 NR NR (18–70) 19 25 ≥3a 42.0 64.0 Alternaria
Gungor et al. [15] USA Unclear 62 NR ≥18 34 28 unclear 85.3 78.6 Ragweed
Wood et al. [24] USA Hospital 120 22 (18) 32 (18–65) 48 32 ≥3b 79.0 91.0 Cat
Pastorello et al. [21] Italy Hospital 91 48 (53) NR (9–57) 70 31 ≥3 and 100,000BU/ml 98.0 70.0 Grass,mugwort, birch, pellitory, Dermatophagoides pteronyssinus
Petersson et al. [23] Sweden Hospital 69 48 (70) 27 (14–53) 36 33 ≥0.5c 97.0 70.0 Birch and timothy grass
Pepys et al. [22] UK Hospital 141 NR NR 72 64 ≥1 68.1 84.4 Sweet vernal, cocksfoot, meadow fescue, rye, timothy, meadow
  1. NR not reported
  2. aOf the size of negative control
  3. bOf the size of negative control plus 1.5 the size of positive control
  4. cThe size of positive control