Table 1 Characteristics of studies reporting primary outcome (skin prick testing)
Study, year | Country | Setting | Sample size | No. of males (%) | Mean age (range), years | Nasal provocation positive | Nasal provocation negative | Wheal size cut-off (mms) | Sensitivity, % | Specificity, % | Allergen extracts |
|---|---|---|---|---|---|---|---|---|---|---|---|
Zarei et al. [25] | USA | Clinic | 45 | 21 (47) | 39 (25–66) | 18 | 27 | ≥3a | 100.0 | 74.1 | Cat |
Krouse et al. [14] | USA | Hospital | 37 | NR | NR (18–70) | 15 | 22 | ≥3a | 87.0 | 86.0 | Timothy grass |
Krouse et al. [14] | USA | Hospital | 44 | NR | NR (18–70) | 19 | 25 | ≥3a | 42.0 | 64.0 | Alternaria |
Gungor et al. [15] | USA | Unclear | 62 | NR | ≥18 | 34 | 28 | unclear | 85.3 | 78.6 | Ragweed |
Wood et al. [24] | USA | Hospital | 120 | 22 (18) | 32 (18–65) | 48 | 32 | ≥3b | 79.0 | 91.0 | Cat |
Pastorello et al. [21] | Italy | Hospital | 91 | 48 (53) | NR (9–57) | 70 | 31 | ≥3 and 100,000BU/ml | 98.0 | 70.0 | Grass,mugwort, birch, pellitory, Dermatophagoides pteronyssinus |
Petersson et al. [23] | Sweden | Hospital | 69 | 48 (70) | 27 (14–53) | 36 | 33 | ≥0.5c | 97.0 | 70.0 | Birch and timothy grass |
Pepys et al. [22] | UK | Hospital | 141 | NR | NR | 72 | 64 | ≥1 | 68.1 | 84.4 | Sweet vernal, cocksfoot, meadow fescue, rye, timothy, meadow |