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Table 1 Clinical characteristics, lung function values and FeNO of the patients included in the study

From: Filaggrin gene mutations and new SNPs in asthmatic patients: a cross-sectional study in a Spanish population

 

All asthmatic patients (n = 300)

AA (n = 150)

NA (n = 150)

Family history of atopy (%)*

120 (40.0 %)

74 (49.3 %)

46 (30.7 %)

Atopic dermatitis (%)*

15 (5.0 %)

14 (9.3 %)

1 (0.7 %)

Contact dermatitis n (%)

73 (24.3 %)

34 (22.7 %)

39 (26.0 %)

Food allergy (%)*

32 (10.7 %)

28 (18.7 %)

4 (2.7 %)

Drug allergy (%)*

58 (19.3 %)

19 (12.7 %)

39 (26.0 %)

Hypersensitivity to NSAID (%)*

34 (11.3 %)

6 (4.0 %)

28 (18.7 %)

Psoriasis (%)

4 (1.3 %)

2 (1.3 %)

2 (1.3 %)

Ichthyosis vulgaris (%)

0 (0.0 %)

0 (0.0 %)

0 (0.0 %)

Lung function values mean ± SD

 FVC (%)*

97.2 ± 16.0

100.9 ± 13.0

93.6 ± 17.9

 FEV1 (%)*

93.0 ± 17.5

96.4 ± 14.2

89.7 ± 20.0

 FEV1/FVC*

74.7 ± 8.6

76.3 ± 8.0

73.0 ± 8.8

 Post-bronchodilator FEV1 improvement (%)

12.81 ± 9.2

12.56 ± 8.5

13.1 ± 9.8

 PEF (%)*

95.0 ± 20.7

99.7 ± 18.2

90.3 ± 22.0

 MMEF (%)*

63.4 ± 25.7

69.8 ± 21.1

57.1 ± 28.3

 FeNO (ppb) mean ± SD*

32.3 ± 30.8

38.0 ± 35.3

26.6 ± 24.2

  1. AA Allergic Asthma group, NA Non-allergic Asthma group, NSAID non-steroidal anti-inflammatory drugs, FVC Forced Vital Capacity, FEV1 Forced Expiratory Volume in 1 s, PEF forced expiratory flow, MMEF maximal mid-expiratory flow, FeNO exhaled nitric oxide
  2. * p < 0.05