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Table 5 Spirometry and exhaled nitric oxide values in patients with non-allergic asthma, according to the 1741A > T SNP

From: Filaggrin gene mutations and new SNPs in asthmatic patients: a cross-sectional study in a Spanish population

Average per genotype

1741A > T

AA (n = 296) mean ± SD

AT (n = 4) mean ± SD

p

FVC (%)*

97.5 ± 15.8

75.3 ± 13.7

0.006

FEV1 (%)*

93.3 ± 17.4

72.9 ± 9.5

0.020

FEV1/FVC

74.8 ± 8.6

69.2 ± 7.3

0.20

Post-bronchodilator FEV1 improvement (%)

12.8 ± 9.2

13.1 ± 5.8

0.94

PEF (%)*

95.5 ± 20.5

63.5 ± 8.0

0.002

MMEF (%)

63.8 ± 25.7

38.9 ± 14.3

0.055

FeNO (ppb)

32.3 ± 30.9

34.0 ± 24.3

0.91

  1. FVC Forced Vital Capacity, FEV1 Forced Expiratory Volume in 1 s, PEF forced expiratory flow, MMEF maximal mid-expiratory flow, FeNO exhaled nitric oxide
  2. * p < 0.05
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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