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Table 6 Associations of combined variable using all the nonsynonymous SNPs

From: Filaggrin gene mutations and new SNPs in asthmatic patients: a cross-sectional study in a Spanish population

 

Mutant alleles

No mutant alleles

p

FVC (%) (n = 15 vs 285)

87.9 ± 19.2

97.7 ± 15.7

0.011

FEV1 (%) (n = 15 vs 285)

80.5 ± 19.1

93.7 ± 17.1

0.001

FEV1/FVC (n = 15 vs 285)

70.6 ± 9.7

74.9 ± 8.5

0.019

PEF (%) (n = 15 vs 285)

81.3 ± 22.5

95.8 ± 20.4

0.002

MMEF (%) (n = 15 vs 285)

48.8 ± 21.7

64.3 ± 25.7

0.007

Total IgE (IU/mL) (n = 20 vs 380)

120.3 ± 255.7

193.7 ± 390.6

0.028

  1. FVC Forced Vital Capacity, EV1 Forced Expiratory Volume in 1 s, PEF forced expiratory flow, MMEF maximal mid-expiratory flow, FeNO exhaled nitric oxide, IgE Immunoglobulin E
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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