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Table 3 Follow-up cohort – divided by severity of clinical allergy at food challenge in original study

From: Reproducibility of serum IgE, Ara h2 skin prick testing and fraction of exhaled nitric oxide for predicting clinical peanut allergy in children

  

CANA (n = 9)

Anaphylaxis n = 5

P value

Age (years)

Median (min, max)

10.9 (4.5, 17.8)

16.0 (14.0, 17.4)

0.029

Sex (%)

Males

3 (33)

4 (80)

0.266

Parental smokers (%)

Total

2 (22)

0 (0)

0.506

Previous adrenaline required (%)

Total

1 (11)

5 (100)

0.003

Other food allergy (%)

Total

4 (44)

1 (20)

0.580

AR (%)

Total

5 (56)

3 (30)

1.000

AR severity for those with AR—max = 4a

Median (min, max)

4 (2, 4)

3 (1, 4)

0.750

Eczema ever (%)

Total

7 (78)

3 (60)

0.580

Eczema active treatment (%)

Total

4 (44)

1 (20)

0.580

SCORAD for those with visible eczema

Median (min, max)

7.4 (3.4, 24.4)

0.0 (0.0, 0.0)

N/A

Asthma ever (%)

Total

5 (56)

3 (60)

1.000

Current preventer (%)

Total

2 (22)

1 (20)

1.000

Current reliever (%)

Total

5 (56)

2 (40)

1.000

Ara h2 SPT (mm) (min, max)

Median (min, max)

7.0 (2.0, 8.0)

5.0 (3.5, 9.0)

0.541

Peanut SPT (mm) (min, max)

Median (min, max)

8.0 (5.5, 12.5)

6.0 (5.0, 13.0)

0.968

Ara h2 sIgE (kU/L)

Median (min, max)

1.15 (0.41, 14.50)

5.02 (0.80, 22.10)

0.227

Peanut sIgE (kU/L)

Median (min, max)

1.49 (0.32, 23.30)

3.88 (1.01, 21.80)

0.240

FeNO (p.p.b)b

Median (min, max)

28.3 (15.2, 119.2)

55.1 (15.4, 79.5)

0.631

  1. Italics indicate statistical significance P < 0.05
  2. AR allergic rhinitis; SCORAD SCORing Atopic Dermatitis; CANA clinical allergy not anaphylaxis; SPT skin prick test; sIgE serum-specific IgE; FeNO fraction of exhaled nitric oxide
  3. a For determination of rhinitis severity, see ‘‘Methods’’ section
  4. b Only 7 individuals in the CANA group were able to perform FeNO, while all 5 individuals in the anaphylaxis group were able to perform FeNO