From: Systematic review of outcome measures in pediatric eosinophilic esophagitis treatment trials
Konikoff [18] | Schaeffer [19] | Dohil [20] | Assa’ad [21] | Spergel [22] | Gupta [23] | Page [25] NCT01458418 | Di Nardo [26] NCT01846962 | Teva Pharm [27] NCT00635089 | McGuire Davis [28] NCT01821898 | Heine [24] | |
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Esophageal eosinophilia | X | X | |||||||||
Endoscopic features | X | X | |||||||||
Modified endocscopy tool | X | X | |||||||||
Histologic features | X | X | |||||||||
Histology Scoring Tool | X | ||||||||||
Severity score for endoscopy and histology | X | ||||||||||
Clinical symptoms | X | ||||||||||
Predominant symptom assessment scores (patient report) | X | ||||||||||
“Clinical Response” (combined patient report and physician assessment) | X | ||||||||||
Symptom scoring tool | X | X | |||||||||
EoE symptom scoring tool | |||||||||||
Pediatric EoE symptom severity module | X | ||||||||||
CHQ scores | X | ||||||||||
PedsQL | X | ||||||||||
Genotypic features | X | ||||||||||
Blood eosinophil counts | X | ||||||||||
Immune features | X | X | |||||||||
Proteonomic features | X | X | X | ||||||||
Profile of durability of response to treatment | X | ||||||||||
Adverse events | X |